Etiology and Pathogenesis of Periodontal Disease Flashcards
What are some common infections in the oral cavity?
Caries Periapical Lesions Fungal Viral Abcesses Periodontal
two basic forms of periodontal diseases are
Gingivitis
Periodontitis
How much of attached gingiva do you loose annually w/ periodontitis?
0.1 eh… inches….
Nonspecific accumulation of plaque causes?
Gingivitis
What are the three things required for a disease?
- ) Microbial plaque
- ) Genetics
- ) Acquired/Environmental factors
What was the 70’s theory to periodontal disease?
Direct plaque was related to increased severity of disease
Etiology of Periodontal disease to cause microbial plaque (5)
Bacteria Fungus Protozoa Virus Mycoplasm
What two things are required for periodontal disease?
Dental Plaque
Endotoxins
What is calculus?
Dead bacteria that have been mineralized
Benefits of a biofilm?
Commuication
Quorum sensing
Resistant to antibiotics and immune response
Bacteria found in the red complex.
Porphyromonas gingivalis
Bacteroids (Tannerella) forsythus
Treponema denticola
What complex are sreptococcus spp. found?
Yellow complex
Which complex is A.a. found?
Green complex
Bacteria attach directly to the?
Pellicle
The pellicle is composed of?
Salivary proteins
What are the 2 regulatory components in G - Quorum sensing
Transcriptional activator protein (R Protein)
AHL molecule
What does the fluid gradient provide in a biofilm?
Flow of nutrients and bacterial communication
Where is the most common location for sub-gingival plaque?
Posterior distal mid-buccal
Is there a relation between poor oral hygiene and the risk of developing periodontitis?
Eh, not really
What must always occur before periodontitis?
Gingivitis
name 3 that help prevent against phagocytosis
Fimbrea
Capsule
Endotoxin
What is the main thing that prevents infection?
Intact epithelium