Ethics of Genomics Flashcards
1
Q
What is CRISPR?
A
An enzyme found in bacteria (as part of its immune system to fight viruses).
2
Q
What are CRISPR sequences?
A
Collections of viral code.
3
Q
What are sequences of DNA in CRISPR called?
A
Spacers.
4
Q
What do spacers do?
A
Turns into RNA and cleaves viral DNA.
5
Q
What is the CRISPR-CAS9 enzyme?
A
An enzyme that can target specific genes.
6
Q
What can the CRISPR-CAS9 enzyme be modified to do?
A
- Silence gene expression. 2. Activate gene expression.
7
Q
What were the major points of the Hunger Winter? (2)
A
- Those exposed to it had differed in their gene regulation such that they were more predisposed to diseases. 2. There was evidence of inter-generational effects.
8
Q
What is the Barker Hypothesis?
A
That there are fetal origins to adult disease.
