Ethanol and the CNS Flashcards by Mateusz Glok | Brainscape

Q

What is the strongest bond ethanol is capable of making? What are the implications?

A

Hydrogen bond

Low affinity binding - high (mM) concentrations required for biological action

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Q

What is a likely target of acohol-based general anaesthesia?

A

Excitory (Glutamate) and Inhibitory (GABA and Glycine) neurotransmitters

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Q

Neurotransmitters bind to the extracellular domain of the Cys-loop Receptors (T/F)

A

True

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Q

Ethanol and other and other allosteric regulators bind to the transmembrane domain of the Cys-loop receptors (T/F)

A

True

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