Etc Flashcards

1
Q

NADH carries

A

2 e and 1 H+

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2
Q

NADH reversible?

A

Yes

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3
Q

FADH (FMNH) carries

A

1 e and 1 H+

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4
Q

FADH2 (FADH2) carries

A

2 e and 2 H+

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5
Q

FAD/FMN reversible?

A

tightly bound to proteins

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6
Q

FAD and FMN reduction potential

A

vary significantly with protein microenvironment

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7
Q

*QH carries

A

1 e and 1 H+

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8
Q

QH2 carries

A

2 e and 2 H+

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9
Q

coenzyme Q reversible?

A

yes

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10
Q

hemes carry

A

1 e-

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11
Q

heme reversible?

A

tightly bound or covalently bonded to proteins

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12
Q

cytochrome

A

protein with bound heme

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13
Q

Fe-S clusters carry

A

each Fe in an Fe-S cluster can carry 1 e

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14
Q

Fe-S clusters reversible?

A

covalently bonded to proteins by cysteine side chain sulfur ligands

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15
Q

Cu centers carry

A

1 e

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16
Q

Cu centers reversible?

A

covalently bonded to proteins by cysteine side chain sulfur ligands

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17
Q

intermembrane space charge

18
Q

matrix charge

19
Q

what does the matrix contain

A

PDH, enzymes of the citric acid cycle, FA degradation pathways

20
Q

complex 1 input substrate

21
Q

complex 1 output e-carrier

A

coenzyme Q

22
Q

complex 1 number of H+ pumped to P side

23
Q

complex 1 number of H+ pumped to QH2

24
Q

complex 2 input substrate

25
Q

complex 2 output substrate

A

coenzyme Q

26
Q

complex 2 number of H+ pumped

27
Q

complex 3 input substrate

A

coenzyme Q

28
Q

complex 3 output substrate

A

Cytochrome C

29
Q

complex 3 number of H+ pumped to P side

30
Q

complex 4 input substrate

A

cytochrome c

31
Q

complex 4 output e carrier

32
Q

complex 4 number of H+ pumped to P side

33
Q

order of ETC cofactors

A
  1. NAD
  2. FAD/FMN
  3. Coenzyme Q
  4. Hemes
  5. Fe-S clusters
  6. Cu clusters
34
Q

ways that NADH can enter the ETC

A

Malate/Asp
Lactate shuttle
TCA

35
Q

ways that FADH2 can enter the ETC

A

TCA
Glycerol phosphate shuttle

36
Q

which verision of coenzyme Q is fullly oxidized

A

ubiquinone

37
Q

which verision of coenzyme Q is fully reduced

38
Q

which verision of coenzyme Q is partly reduced

A

semiquinone

39
Q

P/O ratio

A

ATP produced per O2 reduced

40
Q

% effiency

A

eoutput/einput or delta g transport/delta g hydrolysis

41
Q

delta G of moving a proton across the membrane

A

+ 18.9 kJ/mol

42
Q

how many H+ pumped per NADH