Estrogens and Progestins Flashcards
Potent, orally active estrogen
Ethinyl estradiol
C17 esters that must be hydrolyzed to release free estradiol for biological activity; administered IM or SC
Estradiol propionate, estradiol benzoate
Non-steroidal estrogen; one of the most potent and efficacious orally active estrogens
DES
Progestin with androgenic activity
Norethandrolone
Progestin with anti-androgenic activity
Cyproterone acetate
Progestin with anti-androgenic and anti-mineralocorticoid activities
Drospirenone
Pure progestins
Norgestimate, Promegestone
The major progestin used in replacement therapy in post-menopausal women. Also used as a contraceptive. It is given IM every 2-3 months to induce amenorrhea
Medroxyprogesterone acetate
Phytoestrogen
Genistein