Estrogen Progesterone Androgens Flashcards
1
Q
various types of estrogens in body
A
estradiol premenopausal ovaries
estrone postmenopausal peripheral tissue frm androstendione
estriol pregnancy placenta
2
Q
primary indication for HRT in postmenopausal
A
vasomotor instability vaginal atrophy (local)
3
Q
E comined with P because
A
combn reduces risk of endometrial ca
hysterectomy no need
4
Q
E dose amount in HRT and oral contraceptives
A
more in contraceptives
5
Q
synthetic E have prolonged action than natural
A
y
natural:estradiol
synthetic : mestranol , ethinyl estradiol
6
Q
adr of E
A
breast tenderness nausea htn thromboembolism peripheral edema MI endometrial and breast ca
7
Q
raloxifene has ag or anta activity on endometrium
A
antagonist on endometrium
