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1
Q

Explain the importance of nitrogen-containing substances in biological systems (25)

A

1)

  • enzymes made from amino acids which contain nitrogen. (describe funstion of DNA helicase, DNA polymerase and ligase)
  • these enzymes are important for DNA replication in mitosis (describe mitosis and why it is important)

> DNA enzymes
important for DNA replication in mitosis

2)

  • Proteins are polymers formed of sequences of amino acids which contain nitrogen. (describe structure of proteins)
  • An example of an important protein is haemoglobin (describe it’s structure, co-operative binding, unloading + loading of oxygen, bohr effect and why haemoglobin is important)

> proteins
important protein is hemoglobin

3)

  • Ribosomes are cell organelles made up ofproteinswhich form the 70s and 80s ribosomal subunits. These proteins contain nitrogen. (describe what the ribosome does and its structure etc)
  • the ribosome is important because it catalyses the formation of peptide bonds betweenthis amino acidsto form proteins. For example, haemoglobin. (explain importance of haemoglobin)

> ribosomes
important for producing proteins (haemoglobin)

4)

  • DNA and RNA are made of monomer nucleotides made of a sugar, base and phosphate. The base contains nitrogen. (describe complimentary base pairing, how they H bond etc)
  • Genetic code is degenerate, meaning 3 bases will code for 1 amino acid. In this code mutations can occur, for example a point mutation which is the change of a single base. (explain why this is important in adaptions which could be advantageous - higher reproductive success etc)

> DNA and RNA have bases containing nitrogen
important because mutation in bases leads to variation etc

5)

  • enzymes as biological catalysts (structure, induced fit, specificity)
  • specificity important in digestion (endopeptidases etc, faster absorption to rebuild new amino acids and proteins etc)

> enzymes contain nitrogen
importance in digestion

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2
Q

Explain the importance of diffusion in organisms (25)

A

X

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3
Q

Explain the importance of protein shape in essential processes in organisms (25)

A

1)

  • enzymes in DNA replication
  • important because if DNA replication cannot occur it would affect mitosis (explain how it would affect mitosis by producing haploid daughter cells etc)

2)
- antibodies
- important in stopping viral replication. (can stop complimentary binding of viral attachment proteins to proteins on the surface of the host cell by forming an antibody-antigen complex instead)

> antibodies
important in preventing viral replication

3)

  • enzymes (induced fit theory, lowering activation energy etc)
  • important because glucose can be formed from hydrolysis of maltose catalysed by maltase ( describe how glucose goes on to be used in glycolysis)

> enzymes (general, maltase)
produces glucose for glycolysis

4)

  • shape of pyruvate translocase in mitochondrial membrane which allows active transport of pyruvate across mitochondrial membrane (explain changes that occur in enzyme)
  • importantance of pyruvate entering for link eaction to form acetate to combine with CoA to form aceyl CoA to combine with oxaloacetate to form citrate for Krebs cycle

> enzyme as carrier protein (pyruvate translocase)
importance in link reaction –> Krebs cycle

5)

  • haemoglobin (talk about structure, unloading and loading, bohr effect etc)
  • importance of getting oxygen to respiring cells (oxidative phosphorylation, oxygen as terminal electron acceptor)

> haemoglobin
oxidative phosphorylation –> terminal e- acceptor

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4
Q

Explain the importance of movement in living organisms (25)

A

X

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5
Q

?

A
  • relate to thing in question

- how thing above effects this

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