Esophagitis/GERD Flashcards

1
Q

What is the MCC of Esophagitis?

A

GERD

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2
Q

What is the MCC of Esophagitis in Immunocompromised patients?

A

Candida
CMV
HSV

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3
Q

Which medications can cause esophagitis?

A
  1. NSAIDS
  2. BB
  3. CCB
  4. Bisphosphonates
  5. Vitamin C
  6. Iron supplements
  7. Potassium Cl
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4
Q

What are some risk factors to Esophagitis?

A
  1. Pregnancy
  2. ETOH use
  3. Smoking
  4. Chocolate
  5. Spicey food
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5
Q

What is the best way to diagnose Esophagitis?

A

Upper endoscopy

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6
Q

A patient’s upper endoscopy revealed linear yellow-white plaques. How would you manage this patient?

A

Candida:
PO Fluconazole 1st line

-Voriconazole; Caspofungin 2nd line

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7
Q

A patient’s upper endoscopy revealed small, deep ulcers. How would you manage this patient?

A

HSV:
Acyclovir 1st line

-Foscarnet 2nd line

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8
Q

A patient’s upper endoscopy revealed large superficial shallow ulcers. How would you manage this patient?

A

CMV:
Gangcylovir 1st line

–Valganciclovir; Foscarnet 2nd line

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9
Q

Which esophagitis is associated with multiple corrugated rings seen on endoscopy?

A

Eosinophilic esophagitis

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10
Q

How do you manage a child with eosinophilic esophagitis?

A
  • Remove foods that incite an allergic response

- Inhaled corticosteroids WITHOUT a spacer

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11
Q

How would you manage a patient with pill-induced esophagitis?

A
  • Instruct patient to take pills with at least 4 ounces of water
  • avoid recumbency for at least 30-60 min after taking their pills
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12
Q

A patient has ingested drain cleaner on accident and is suffering from Caustic esophagitis. What is the next best step in managing this patient?

A

Endoscopy is used to determine the extent of damage and to look for complications: perforation, stricture, esophageal fistula

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13
Q

A patient has ingested drain cleaner on accident and is suffering from Caustic esophagitis. What is the best management for this patient?

A

Supportive, pain medications, IV fluids

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14
Q

What are some alarm sxs in GERD patients?

A
  1. Dysphagia
  2. Odynophagia
  3. Weight loss
  4. Bleeding
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15
Q

What is the gold standard for diagnosing GERD?

A

24 Hr ambulatory monitoring

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16
Q

What the best initial test used for diagnosing GERD?

A

Endoscopy

17
Q

What does an Esophageal manometry reveal for a patient with GERD?

A

Decreased LES pressure

18
Q

What is Stage 1 in managing GERD?

A

LIfestyle modifications:

  1. Elevation fo the head of the bed by 6 inches
  2. Avoid for 3 hours after eating
  3. Eat small meals
  4. Avoid certain foods
  5. Decrease fat and ETOH intake
  6. Weight loss
  7. Smoking cessation
19
Q

What is Stage 2 in managing GERD?

A

“As needed” pharmacological therapy:

  • Antacids and OTC H2 receptor blockers
  • If there are alarm sxs, an upper endoscopy is the next step
20
Q

What is Stage 3 in managing GERD?

A

Initiation of scheduled pharm therapy:

  • H2RA
  • PPI & prokinetic agents (Cisapride)

*PPI are the DOC in moderate-severe disease

21
Q

What is the management in refractory GERD?

A

Nissen fundoplication

22
Q

What is the DOC in moderate-severe GERD?

A

PPIs