Colorectal cancer

Question 1

Which polyps are not considered cancerous and are due to IBD?

Answer 1

Pseudopolyps/inflammatory polyps

Question 2

Which type of polyps make up 90% of all polyps overall?

Answer 2

Hyperplastic: low risk for malignancy

Question 3

Which type of polyps make up 10% of polyps and have an average of 10-20 years before becoming cancerous?

Answer 3

Adenomatous polyps

Question 4

What is a tubular adenoma?

Answer 4

A subtype of Adenomatous polyp:

• nonpedunculated
• MC of the 3 subtypes of adenomatous polyps
• Least risk of becoming cancerous

Question 5

Which polyp has an intermediate risk of becoming cancerous?

Answer 5

Tubulovillous (mixture)

Question 6

Which polyp has the highest risk of becoming cancerous?

Answer 6

Villous adenoma

-tends to be sessile

Question 7

How is Stage I-III colon cancer managed?

Answer 7

Surgical resection

Question 8

Which stages of colon cancer are managed with a surgical resection?

Answer 8

Stage I-III

Question 9

How are Stage III and Metastatic colon cancer managed?

Answer 9

Chemotherapy is the mainstay* of Tx

5-FU (Fluorouracil)

Question 10

What are the USPSTF guidelines for the screening of colon cancer

Answer 10

3 approaches:

1. High sensitivity fecal occult testing annually
2. Flex sigmoidoscopy every 5 years + fecal occult testing every 3 years
3. Colonoscopy every 10 years from age 50-75