ESOHPHAGUS Flashcards
Dx of esophageal cancer
esophageal ultrasound
For distant met PET/CT
Early stage esophageal cancer
treatment of stage I and II esophageal cancer
Rx surgery This is stages I and II
It includes up to T3 if N0, but is mostly T1-2, N0-1
Role of adjuvant therapy is “controversial”
Neoadjuvant can be chemo or chemo/rad
If no neoadjuvant Rx then should get adjuvant chemo post op.
All the rest also “Controversial” But can do neoadjuvant and if good response go on to resection
Transhiatal, Ivor Lewis, or McKeown—no difference in outcome
If endoscopic perf above cancer and no mets—do acute resection
If endoscopic perf above cancer and mets—do stent, chest drainage, and Chemo/RT
Maximum resectable esophageal cancer
> 5cm from cricopharyngeus,
T1-3N+
or
T4aN0,
Need 15 LNs
neoadj for
T1bN+
T1b submucosa
or
> =T2
T2 Muscularis
(can forego if non-cervical, low-risk,
Not resectable
“Invading the linings is ok: pericardium, pleura, diaphragm”
T4 BBBBBB NO!
b. aorta!, vertebae, trachea
T4 a YES!
STILL GO FOR CURE
a: pleura, pericardium, diaphragm -
NO
supraclavicular node
multistation nodes:
extraregional lymph node spread:
paraaortic
or
mesenteric
PREVIOUSLY thought that celiac area remote from the primary tumor (eg, for a SCC in the upper or middle thoracic esophagus) was previously thought to be a sign of unresectability and considered metastatic disease [4].
However, celiac nodal metastases are scored as regional nodal disease in the new 2010 edition of the TNM staging system, regardless of the primary tumor location or histology, and they no longer carry the connotation of distant metastatic disease [1].
Nevertheless, prognosis is poor in such cases, even if the primary tumor is located in the distal esophagus or EGJ [11,12]. In one series, the two-year survival rate of patients with celiac node involvement who underwent surgery as a component of therapy was approximately 10 percent [12].
-ivor-lewis
laparotomy
R thoracotomy
Anastamosis at or above azygos
- inadequate proximal margin for mid-esophageal tumors
McKeown
3-hole with cervical anastamosis
nodal staging
N0 No regional lymph node metastasis
N1 Metastasis in 1-2 regional lymph nodes
N2 Metastasis in 3-6 regional lymph nodes
N3 Metastasis in seven or more regional lymph nodes
Medical therapy for esophageal varices
Antibiotics! ( for portal hypertension and bacterial peritonitis risk)
Octreotide
Proton pump inhibitor (of course, not if hypotension)
Minnesota tube
Replaced Blakemore tube because another pork to clear saliva
Passing to stomach instill 40 – 50 mL and confirm on x-ray that you’re in the stomach
Then instill 250 mL total gastric balloon
Put on traction with 2 L fluid bag
Is still bleeding:
Men inflate the esophageal balloon to 30 mmHg
(can stay inflated overnight?)
Mesocaval shunt
Nonselective
Eight – 10 mm graft
Between the superior mesenteric vein (this is portal blood) and IVC
So the SMB side first because it is more interior
So the vena cava second because it tolerates a Satinsky side biting clamp
Good for emergency
Bad for transplant
VEIN directly responsible for esophageal varices
Coronary vein
Anastomosis of left and right gastric names
Near lesser curves of the stomach
Medication used for esophageal varices bleeding
Octreotide
Do not use vasopressin
Vasopressin can worsen heart failure
PPI
Beta blocker if pressure can tolerated
Ceftriaxone
What is the basic moved to expose the esophagus to evaluate perforation
Take down the left inferior pulmonary ligament
Watch out for the inferior pulmonary vein
(this is the same move for clamping the aorta from left thoracotomy for trauma)
Management of late esophageal perforation
Spit fistula
You’re not going to salvage the esophagus