BREAST Flashcards

1
Q

With special management doesn’t triple negative breast cancer need

A

Add Taxol

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2
Q

Management of locally advanced disease Chest wall

A

XRT

Also use XRT to the axilla if four or more nodes

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3
Q

When do use neoadjuvant

A

therapy Triple negative
Her2-nu +
Locally advanced
Inflammatory breast cancer

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4
Q

When do you use adjuvant therapy

A

Greater than 1 cm

Node positive

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5
Q

When you get genetic testing

A

Breast cancer under the age of 45

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6
Q

What is new adjuvant chemotherapy regimen

A

Three cycles:

Adriamycin
Cisplatin

With Taxane

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7
Q

Management of breast metastasis to the liver or the long

A

One isolated met with extremely favorable clinical scenario i.e. no other distant disease
On extensive workout

Consideration given to metastasis resection

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8
Q

Treatment for first trimester breast-cancer

A

Mastectomy

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9
Q

Breast cancer chemotherapy

A

TAC

Taxane
Adriamycin
Cis-platinum

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10
Q

Contraindications from normal breast cancer management in pregnancy

A

No taxane
No methotrexate

No blue dye

No tamoxifen

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11
Q

Management is an 80-year-old with breast cancer

A

Consider no chemotherapy if life expectancy less than or equal to five years

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12
Q

Significance in screening of breast cancer luminal a

A

Association with BRCA2?

MRI six months
Mammogram six months

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13
Q

Decreased breast cancer risk with bilateral mastectomy

A

Decrease cancer risk 95%

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14
Q

Decreased overbearing cancer with bilateral oophrectomy

A

Decreased cancer risk 80%

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15
Q

Cancer is associated with the BRCA II

A

MALE breast cancer
prostate!

Melanoma!
Pancreas cancer
ovarian cancer I>II (2 is the male and males do not have ovaries)

Uterine papillary serous carcinoma

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16
Q

Worst prognosis breast cancer

A

Basal

This is triple negative

(three leaves of the basil plant)

BRCA I is worse then BRCA II

17
Q

Management of a breast abscess six months postpartum

A

Aspirate
Antibiotics

Pump infected side

18
Q

“Medullary” breast cancer

A

Rapidly enlarges

Due to lymphocytic reaction

Axilla notes are not cancer but still take them out

19
Q

Tubular carcinoma of the breast

A

subtype of invasive ductal carcinoma

usually small (about 1 cm or less)

made up of “tubules.”

20
Q

Breast cancer risk with atypical doctoral hyperplasia

A

1.6% in 5 five years

20% lifetime

This qualifies risk factor for MRI

21
Q

What is the risk of developing breast cancer with LCI S

A

60% DUCTILE carcinoma

40% lobular carcinoma

22
Q

Margins for a pheloides tumor

A

Coach says 2 cm

Possibly one centimeter

23
Q

Drugs that can cause gynecomastia

A

Spironolactone
Digitalis
Marijuana

24
Q

Who is not qualified for Z11

A

Patients undergoing mastectomy

25
Q

BRCA II

A

Prostate (Male breast cancer)
Pancreas
Melanoma
Ovaries

26
Q

Pagets is associated with what breast cancer

A

Adenocarcinoma

27
Q

Anal ulcer is treated how if it is found to be squamous cell carcinoma

A

Niagara protocol

5-FU (because everyone gets 5-FU

mitomycin C
“Mighty mouse is here to save the day if anus cancer”

Coach says 3.5 gray
4.5 gray uptodate

28
Q

Breast cancer risk factors to ask you about in the history

A
Agent menarche
Age of menopause
Pregnancy / breast feeding
Estrogen exposure - hormone replacement
Birth control pills
Radiation exposure
Family history
History of breast lesion or biopsy
29
Q

Breast cancer chemotherapy

And modifications for pregnancy

A

Taxane - NO for pregnancy

Adriamycin (watch the heart with cardiomypathy of pregnacy)

Cis-platinum

Herceptin - NO for pregnancy

30
Q

Management of recurrent pheloids tumor

A

Re-excise

31
Q

neo adjuvant therapy for what breast cancer

A

Inflammatory
Advanced local disease (greater than 5 cm)
Clinically positive nodes

(possibly for familial)

32
Q

What is basic Z-11

A

1-2 nodes positive

T1 (0.1 - 2 cm)
T2 (2.1 - 5 cm)
Already going to get whole breast radiation from lumpectomy

does NOT apply to patients getting a mastectomy

33
Q

Work up with patient history of breast cancer and increased calcium

A

Get a phosphorus level with the calcium.

Phosphorus level will be elevated as well if this is an metastatic bone disease

If restaging negative:
Get PTH