BREAST Flashcards

1
Q

With special management doesn’t triple negative breast cancer need

A

Add Taxol

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2
Q

Management of locally advanced disease Chest wall

A

XRT

Also use XRT to the axilla if four or more nodes

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3
Q

When do use neoadjuvant

A

therapy Triple negative
Her2-nu +
Locally advanced
Inflammatory breast cancer

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4
Q

When do you use adjuvant therapy

A

Greater than 1 cm

Node positive

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5
Q

When you get genetic testing

A

Breast cancer under the age of 45

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6
Q

What is new adjuvant chemotherapy regimen

A

Three cycles:

Adriamycin
Cisplatin

With Taxane

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7
Q

Management of breast metastasis to the liver or the long

A

One isolated met with extremely favorable clinical scenario i.e. no other distant disease
On extensive workout

Consideration given to metastasis resection

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8
Q

Treatment for first trimester breast-cancer

A

Mastectomy

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9
Q

Breast cancer chemotherapy

A

TAC

Taxane
Adriamycin
Cis-platinum

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10
Q

Contraindications from normal breast cancer management in pregnancy

A

No taxane
No methotrexate

No blue dye

No tamoxifen

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11
Q

Management is an 80-year-old with breast cancer

A

Consider no chemotherapy if life expectancy less than or equal to five years

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12
Q

Significance in screening of breast cancer luminal a

A

Association with BRCA2?

MRI six months
Mammogram six months

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13
Q

Decreased breast cancer risk with bilateral mastectomy

A

Decrease cancer risk 95%

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14
Q

Decreased overbearing cancer with bilateral oophrectomy

A

Decreased cancer risk 80%

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15
Q

Cancer is associated with the BRCA II

A

MALE breast cancer
prostate!

Melanoma!
Pancreas cancer
ovarian cancer I>II (2 is the male and males do not have ovaries)

Uterine papillary serous carcinoma

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16
Q

Worst prognosis breast cancer

A

Basal

This is triple negative

(three leaves of the basil plant)

BRCA I is worse then BRCA II

17
Q

Management of a breast abscess six months postpartum

A

Aspirate
Antibiotics

Pump infected side

18
Q

“Medullary” breast cancer

A

Rapidly enlarges

Due to lymphocytic reaction

Axilla notes are not cancer but still take them out

19
Q

Tubular carcinoma of the breast

A

subtype of invasive ductal carcinoma

usually small (about 1 cm or less)

made up of “tubules.”

20
Q

Breast cancer risk with atypical doctoral hyperplasia

A

1.6% in 5 five years

20% lifetime

This qualifies risk factor for MRI

21
Q

What is the risk of developing breast cancer with LCI S

A

60% DUCTILE carcinoma

40% lobular carcinoma

22
Q

Margins for a pheloides tumor

A

Coach says 2 cm

Possibly one centimeter

23
Q

Drugs that can cause gynecomastia

A

Spironolactone
Digitalis
Marijuana

24
Q

Who is not qualified for Z11

A

Patients undergoing mastectomy

25
BRCA II
Prostate (Male breast cancer) Pancreas Melanoma Ovaries
26
Pagets is associated with what breast cancer
Adenocarcinoma
27
Anal ulcer is treated how if it is found to be squamous cell carcinoma
Niagara protocol 5-FU (because everyone gets 5-FU mitomycin C "Mighty mouse is here to save the day if anus cancer" Coach says 3.5 gray 4.5 gray uptodate
28
Breast cancer risk factors to ask you about in the history
``` Agent menarche Age of menopause Pregnancy / breast feeding Estrogen exposure - hormone replacement Birth control pills Radiation exposure Family history History of breast lesion or biopsy ```
29
Breast cancer chemotherapy And modifications for pregnancy
Taxane - NO for pregnancy Adriamycin (watch the heart with cardiomypathy of pregnacy) Cis-platinum Herceptin - NO for pregnancy
30
Management of recurrent pheloids tumor
Re-excise
31
neo adjuvant therapy for what breast cancer
Inflammatory Advanced local disease (greater than 5 cm) Clinically positive nodes (possibly for familial)
32
What is basic Z-11
1-2 nodes positive T1 (0.1 - 2 cm) T2 (2.1 - 5 cm) Already going to get whole breast radiation from lumpectomy does NOT apply to patients getting a mastectomy
33
Work up with patient history of breast cancer and increased calcium
Get a phosphorus level with the calcium. Phosphorus level will be elevated as well if this is an metastatic bone disease If restaging negative: Get PTH