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EMATOLOGIA > Esame Erasmus 2022 > Flashcards

Esame Erasmus 2022 Flashcards

1
Q

What kind of blleding is typical of thrombocytopenia:
a. deep cutaneous hematoma
b. Petehias in the skin and mucous membranes
c. Bleeding into the joints
d. Bleeding into the muscles

A

B

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2
Q

All are cause of reactive thrombocytosis, except:
a. Chronic inflamation
b. Essential thrombocytosis
c. Iron deficiency anemia
d. Surgery

A

b. Essential thrombocytosis

Essential thrombocytosis, also known as primary thrombocythemia or essential thrombocythemia, is a disorder characterized by an abnormal increase in platelet production without an underlying cause. It is not considered a reactive thrombocytosis.

Therefore, the correct answer is b

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3
Q

Which of the following is NOT a chronic myeloproliferative disease:
a. Thalessemia
b. Polycythemia rubra vera (PRV)
c. Chronic myelocitic leukemia
d. Primary myelofibrosis

A

a. Thalessemia

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4
Q

In lymphoma the lymph nodes are most commonly:
a. hard, unmovable and painless
b. Elastic, movable and painless
c. Painful and warm

A

b. Elastic, movable and painless

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5
Q

The antibody type in chronic cold agglutin hemolytic disease is:
a. IgG
b. IgM
c. Mixed
d. IgA

A

b. IgM

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6
Q

Fresh frozen plasma is used in:
a. Replacing albumin
b. Replacement of clotting factors when no recombinant factor is available
c. Platelet replacement in thrombocytopenia
d. Replacement of clotting factors

A

b. Replacement of clotting factors when no recombinant factor is available

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7
Q

What applies to chronic lymphacytic leukemia:
a. Causes painful and enlarged lymph nodes
b. Often arises from T cells
c. The course is fast and leads to the death of the patient within 5 years after diagnosis
d. Rarely affects (infiltrates) the bone marrow
e. Non of the above

A

e. Non of the above

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8
Q

Hypersegmented neutrophils are seen in:
a. Chronic myelogenous leukemia (CML)
b. Chronic lymphacytic leukemia (CLL)
c. Iron deficiency anemia
d. Vitamin B12 deficiency

A

d. Vitamin B12 deficiency

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9
Q

What is pseudothrombocytopenia?
a. Decreased platelet count due to analyzer error
b. Increased platelet count due to analyzer error
c. Decreased platelet count due to blood diseases
d. Reduced platelet counts due to their aggregation “in vitro”

A

d. Reduced platelet counts due to their aggregation “in vitro”

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10
Q

What agglutins does a patient with blood group AB have?
a. No agglutins to A or B
b. Anti B agglutins
c. Anti A agglutins
d. Anti A and anti B agglutins

A

a. No agglutins to A or B

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11
Q

What is common complication in the treatment of patients with thalassemia?
a. Iron deficiency
b. Copper deficiency
c. Iron overload
d. Zinc deficiency

A

c. Iron overload

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12
Q

A 34-year-old patient was admitted through the emergency room for severe thrombocytopenia 3x10^9/L and visible petechial bleeding. He received corticosteroid treatment after which platelets rose to 75x10^9/L. What is the most likely diagnosis?
a. Thrombocitic thrombocytopenic purpura
b. Myelodysplastic syndrome
c. Immune thrombocytopenia
d. Acute lymphoblastic leukaemia

A

c. Immune thrombocytopenia

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13
Q

The following five types of leukocytes are normally found in the peripheral blood:
a. Lymphocytes, neutrophils, monocytes, megacaryocytes and basophils
b. Lymphocytes, neutrophils, monocytes, eosinophils and basophils
c. Lymphocytes, neutrophils, monocytes, emyeloids and eosinophils
d. Lymphacytes, monocytes, neutrophils, basophils and lymphoblasts

A

b. Lymphocytes, neutrophils, monocytes, eosinophils and basophils

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14
Q

Which of the following situation will lead to intravascular hemolysis?
a. Group O RBC to group A recipient
b. Group O RBC to group AB recipient
c. Rh + RBC to Rh - recipient
d. Group A RBC to group O recipient

A

d. Group A RBC to group O recipient

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15
Q

The patient with chronic obstructive pulmonary disease has reactive erythrocytosis. What’s the most likely reason?
a. Increased eritropoetin
b. Decreased eritropoetin
c. Decreased plasma volume
d. Polycythemia rubra vera

A

a. Increased eritropoetin

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16
Q

Auer’s rods are present is:
a. Myeloblasts
b. Erythroblasts
c. Monoblasts
d. Lymphoblasts

A

Myeloblasts

17
Q

Treatment for low-risk MDS include, all except:
a. Reduced intensity allo-SCT
b. Lenalidomide
c. Erythropoietin
d. G-CSF

A

a. Reduced intensity allo-SCT

18
Q

Anemia with increased reticulocyte counts is present in:
a. Franconi’s anemia
b. Anemia in renal impairment
c. — chronic inflammation
d. Hereditary spherocytosis

A

d. Hereditary spherocytosis

19
Q

Bence Jones protein rapresents:
a. free light chains

A

Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22–24 kDa.[1] Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström’s macroglobulinemia

20
Q

Diagnosis of CLL is confirmed by:
a. Immunophenotyping
b.
c.
d.

A

a. Immunophenotyping
The diagnosis is confirmed by immunophenotyping of venous blood lymphocytes.

21
Q

In emergencies, the patient may receive a non cross-matched transfusion of which blood group
a. Erythrocytes 0 RhD-neg, Kell neg
b. Full blood KS AB, RhD-neg, Kell-neg
c. Full blood AB. RhD-neg, Kell-pos
d. No answer is correct

A

a. Erythrocytes 0 RhD-neg, Kell neg

22
Q

The following hemostatic parameter is most commonly prolonged in patients with Hemophilia A:
a. Activated partial thromboplastin time (APT)
b. Platelet count
c. Prothrombin time (PT)
d. Bleeding time

A

a. Activated partial thromboplastin time (APT)

23
Q

Pancytopenia in the peripheral blood is the presenting feature except in:
a. Pure red cell aplasia
b. Hypersplenism
c. Aplastic anemia
d. Megaloblastic syndrome
e. Myelodisplastic syndrome

A

a. Pure red cell aplasia

24
Q

Which of the following is not true regarding erythropoietin?
a. 90% of hormone is made of liver
b. High altitude dwellers have more EPO levels
c. Levels in blood are high in polycythemia secondary to tumor
secreting EPO but are low in severe renal disease and polycythemia vera
d. Its gene has hypoxia response elements

A

a. 90% of hormone is made of liver

25
Q

PT/INR assay is sensitive for which pathway of the coagulation cascade:
a. extrinsic coagulation
b. platelet functions
c. intrinsic coagulation
d. fibrinolysis

A

a. extrinsic coagulation

26
Q

Hemophilia A is an inherited disease that is treated with:
a. fresh frozen plasma
b. Cryoprecipitate
c. Factor VIII
d. Factor IX

A

c. Factor VIII

27
Q

Bortezomib acts by:
a. Proteosome inhibition
b. Microsome inhibition
c. Lysosome inhibition
d. Ribosome inhibition

A

a. Proteosome inhibition

28
Q

Hyperviscosity in multiple myeloma is commonly seen with which paraprotein:
a. IgA
b. IgM
c. IgD
d. IgG

A

b. IgM

29
Q

Which of the following is not true about AIHA?
a. May be associated with IgM antibodies in serum
b.Associated with pernicious anemia
c. It may be due to drugs
d. May complicate B-cell CLL

A

b.Associated with pernicious anemia

30
Q

Diagnosis of acute lymphoblastic leukemia in bone marrow requires:
a. 15% blasts
b. 10% blasts
c. 20% blasts
d. 30% blasts

A

c. 20% blasts
[UpToDate]

31
Q

Allergic reactions are often associated with increased values of:
a. Eosinophils
b. Monocytes
c. Neutrophils
d. Lymphocytes

A

a. Eosinophils

32
Q

What is most likely diagnosis regarding the full blood count below?
a. Chronic myelocitic leukemia
b. Infection
c. Chronic lymphocytic leukemia
d. Acute myeloid leukemia

A

a. Chronic myelocitic leukemia
(leucocitosi, anemia, leftshift
nell’acuta si troverebbe invece piastrinopenia, neutropenia, leucopenia o leucocitosi e left-shift)

33
Q

Correct for Polycythemia Vera:
a. EPO levels are raised
b. V617F is seen in > 90% of patients
c. Splenomegaly may be presenting (…)
d. …agenic Pruritus is a distingu …

A

d. …agenic Pruritus is a distingu …

34
Q

Extravascular hemolysis …
a. Splenomegaly
b. Jaundice
c. INcreased hemoglobin
d. INcreased LDH

A

a. Splenomegaly

EMATOLOGIA (4 decks)

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