Erythropoiesis Flashcards
when does primitive erythropoeisis occur in the embryonic yolk sac ?
21st day
when does it move to the AGM ?
between the 30th-40th day
specifically the vitelline artery
functions of red blood cells
1) transport of O2 from lungs to the tissues
2) transport of waste products like CO2 from tissues to lungs
3) determination of a persons blood type
4) regulation of body temperature
5) transport of nutrients
6) haemoglobin acts as a buffer in ph regulation
lifespan of platelets
10 days
list the phagocytes you know
1) neutrophils
2) basophils
3) eosinophils
4) monocytes
what is the first recognizable erythrocyte precursor in the bone marrow ?
the pronormoblast
mitotic stage of division ends in what stage ?
polychromatic eryhtroblast/intermediate normoblast
it takes _ days for reticulocytes to become mature RBCs
2 days (48hrs)
the number of cells produced from proerythroblast to mature RBCs is
16
haemoglobin synthesis begins from what stage ?
polychromatic erythroblast
list the stages of erythropoeisis
1) proerythroblast/pronormoblast
2) basophilic erythroblast/early normoblast
3) polychromatic erythroblast/intermediate normoblast
4) orthochromatic E / Late N
5) reticulocyte
6) matured erythrocyte
it takes _ days for development of RBCs from proerythroblast
7 days
nucleus disintegrates in what stage of erythropoiesis & through a process called ?
orthochromic erythroblast stage
process - pyknosis
one pronormoblast gives rise to how many mature red cells ?
16
