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HEMATOLOGY > Erythrocyte Metabolism, Membrane Structure, Function > Flashcards

Erythrocyte Metabolism, Membrane Structure, Function Flashcards

1
Q 
TRUE OR FALSE:
Adenosine Triphosphate (ATP) is produced within the cytoplasm through aerobic glycolysis.
A

FALSE

-Anaerobic glycolysis (Embden-Meyerhof Pathway)

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2
Q

Shortened RBC survival is collectively known as

a. Poikilocytosis
b. Hereditary non-spherocytic hemolytic anemia
c. Hereditary normocytic hemolytic anemia
d. NOTA

A

B. Hereditary non-spherocytic hemolytic anemia

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3
Q

What pathway anaerobically generates energy in the form of ATP?

a. Methemoglobin reductase pathway
b. Hexose-monophosphate pathway
c. Rapoport-luebering pathway
d. Embden-Meyerhof pathway

A

d. Embden-Meyerhof pathway

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4
Q

What pathway provides the main source of rbc energy?

a. Hexose-monophosphate pathway
b. Embden-Meyerhof pathway
c. Methemoglobin reductase pathway
d. NOTA

A

b. Embden-Meyerhof pathway

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5
Q

This pathway provides reduced glutathione that will prevent oxidation denaturation of Hgb

a. Hexose-monophosphate pathway
b. Embden-Meyerhof pathway
c. Methemoglobin reductase pathway
d. NOTA

A

a. Hexose-monophosphate pathway

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6
Q

This pathway generates 2,3-DPG which regulates hemoglobin affinity to oxygen

a. Methemoglobin reductase pathway
b. Hexose-monophosphate pathway
c. Rapoport-luebering pathway
d. Embden-Meyerhof pathway

A

c. Rapoport-luebering pathway

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7
Q

Decreased amount of 2,3 DPG ____ the oxygen affinity of the hemoglobin molecule.

a. Increases
b. Decreases
c. Does not alter
d. Varies

A

a. Increases

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8
Q 
Increased 2,3-DPG: Decreased 02 affinity
Increased 02 Delivery: \_\_\_\_\_\_\_\_
a. Shift to the left
b. Shift to the right
c. Shift mo lang
D. NOTA
A

b. Shift to the right

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9
Q

TRUE OR FALSE:

RBC cytoplasm K+ concentration is higher than plasma K+, whereas Na+ and Ca2+ concentrations are lower

A

TRUE

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10
Q

Which of the following helps maintain RBC shape?

a. Cytoskeletal proteins
b. Membrane phospholipids
c. GPI anchor
d. Glycocalyx

A

a. Cytoskeletal proteins

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11
Q

Which of the following is a water transporter?

a. Glut-1
b. Aquaporin 1
c. Ca2+ ATPase
d. NOTA

A

b. Aquaporin 1

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12
Q

It carries the peptide-defined M and N determinants

a. Glycophorin A
b. Glycophorin B
c. Glycophorin C
d. NOTA

A

a. Glycophorin A

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13
Q

This pathway occurs through a diversion of glucose catabolism.

a. Methemoglobin reductase pathway
b. Hexose-monophosphate pathway
c. Rapoport-luebering pathway
d. Embden-Meyerhof pathway

A

b. Hexose-monophosphate pathway

- also known as Pentose phosphate shunt

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HEMATOLOGY (3 decks)

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