ERYTHROCYTE DESTRUCTION PPT

Question 1

ERYTHROCYTE DESTRUCTION

Answer 1

• Macrophage-Mediated Hemolysis
  (Extravascular Hemolysis)
  -Mechanical Hemolysis (Fragmentation or
  Intravascular Hemolysis)

Question 2

Macrophages are able to recognize senescent cells and distinguish them from younger cells; thus the older cells are targeted for ingestion and lysis.

Answer 2

Macrophage-Mediated Hemolysis
(Extravascular Hemolysis)

Question 3

The vascular system can be traumatic to RBCs, with turbulence occurring in the chambers of the heart or at points of bifurcation of vessels. Small breaks in blood vessels and resulting clots can also trap and rupture cells.

Answer 3

Mechanical Hemolysis (Fragmentation
or Intravascular Hemolysis)

Question 4

The intravascular rupture of RBCs from purely mechanical or traumatic stress results in fragmentation and release of the cell contents into the blood; this is
called

Answer 4

Mechanical Hemolysis (Fragmentation
or Intravascular Hemolysis)