Erythema multiforme

Question 1

define Erythema multiforme ?

Answer 1

an acute hypersensitivity reaction of the skin and mucous membranes triggered by infections.

Question 2

classical infection causing this condition?

Answer 2

mycoplasma pneumonia

Question 3

other causes of erythema multiforme?

Answer 3

o	Idiopathic – 50% of the time
o	Drugs 
o	Inflammatory - e.g. rheumatoid arthritis, SLE, sarcoidosis, ulcerative colitis 
o	Malignancy
o	Radiotherapy

Question 4

whom is erythema multiforme most common in?

Answer 4

mainly in children and young adults

Question 5

main features of erythema multiforme ?

Answer 5

• Classic target (target) lesions
• Vesicles/bullae
• Lesions are often symmetrical
• Distribution over the arms and legs including the palms, soles and extensor surfaces

Question 6

what investigations are required?

Answer 6

• Usually unnecessary - clinical diagnosis