Erectile Dysfunction

Question 1

What Medications Can Cause Erectile Dysfunction? (8)

Answer 1

.Diuretics (used for high blood pressure, heart failure, kidney disease)

.Antihypertensives

.Fibrates

.Antipsychotics

.Antidepressants

.Corticosteroids

.H2-antagonists

.Anticonvulsants

Question 2

What Are the Risk Factors for Erectile Dysfunction? (7)

Answer 2

.Peyronie’s disease (penis distortion or curvature)

.Priapism (inflammation of the penis)
Depression

.Alcohol use

.Lack of sexual knowledge

.Poor sexual techniques

.Inadequate interpersonal relationships

.Smoking (exacerbates vascular disease and hypertension)

Question 3

What Lifestyle Changes Can Help Improve Erectile Dysfunction? (6)

Answer 3

.Losing weight

.Reducing smoking

.Reducing alcohol intake

.Not taking illegal drugs

.Regular exercise

.Reducing stress

Question 4

What are PDE-5 inhibitors and how do they work for erectile dysfunction?

Answer 4

PDE-5 inhibitors are medications used to treat erectile dysfunction by temporarily increasing blood flow to the penis. They are one of the most widely used and effective treatments.

Question 5

What are the common PDE-5 inhibitors used for erectile dysfunction?

Answer 5

.Sildenafil (brand name: Viagra)

.Tadalafil (brand name: Cialis)

.Vardenafil (brand name: Levitra)

.Avanafil (brand name: Spedra)

Question 6

How long do different PDE-5 inhibitors last?

Answer 6

Sildenafil, Vardenafil, Avanafil work for about 8 hours and are taken ‘on demand.’

Tadalafil lasts up to 36 hours, suitable for longer-term treatment.

Question 7

What are the common side effects of PDE-5 inhibitors? (8)

Answer 7

.Headaches and migraines

.Flushing

.Indigestion

.Nausea

.Vomiting

.Back pain

.Vision disturbances

.Muscle pain

Question 8

Sildenafil:

1. When should it be taken before sexual activity?
2. Time to onset of effect?
3. Duration of action ?

Answer 8

1. Should be taken 1 hour before
2. Onset of effects: 25 minutes
3. Duration: 4-5 hours

Question 9

How does food affect the rate of absorption of sildenafil ?

Answer 9

Rate of absorption reduced by mean of 60 minutes when taken with food.

Question 10

Tadalalfil:

1. When should it be taken before sexual activity?
2. Time to onset of effect?
3. Duration of action ?

Answer 10

1. At least 30 minutes before
2. Time to onset of effect: 16 minutes- 36 hours
3. Duration : up to 4-5 hours

Question 11

What are the contraindications for using PDE-5 inhibitors? (10)

Answer 11

PDE-5 inhibitors should not be used in the following conditions:

.Unstable angina or angina occurring during sexual intercourse (type of chest pain caused by not enough blood going to the muscles of the heart)

.Regular or intermittent use of nitrates (risk of severe hypotension)

.Hypotension (systolic blood pressure below 90 mmHg)

.Recent myocardial infarction

.Recent stroke

.Heart failure

.Uncontrolled arrhythmias

.Uncontrolled hypertension

.Severe hepatic impairment

.Renal impairment