Erectile dysfunction

Question 1

Does erectile dysfunction increase risk of CVD

Answer 1

Yes

Question 2

What is the first line treatment for erectile dysfunction

Answer 2

Oral phosphodiesterase type 5 inhibitor

Question 3

What are some examples of Oral phosphodiesterase type 5 inhibitor

Answer 3

Sildenafil, Avanafil (short acting and occasional use)

Tadalafil - long acting

Question 4

What are some SE of the afils

Answer 4

Vasodilation, headaches, dizziness, GI disorders, vision disorders, arrhythmias

Question 5

What is the contraindication of Oral phosphodiesterase type 5 inhibitor

Answer 5

Recent MI, stroke, avoid if systolic BP is below 90mmHG

Question 6

What are some interactions of Oral phosphodiesterase type 5 inhibitor

Answer 6

Nitrates, CCB, alpha blockers

Question 7

What is the second line treatment of erectile dysfunction

Answer 7

Alprostadil - prostaglandin analogue

Question 8

Where is alprostadil administered

Answer 8

intracavernosal (base of penis), intraurethral or topical application

Question 9

What can Alprostadil cause

Answer 9

Priapism - prolonged erection lasting 4 hours or more - seek medical help

Question 10

Should you use condoms with alprostadil

Answer 10

Yes - to avoid local reactions