Equine eyelid disorders Flashcards
Clinical signs eyelid dysfunction (6)
- Gross tissue distortion
- Ulceration
- Changes in mobility
- Epiphora
- Mucopurulent discharge
- Exposure/irritation keratitis
Eyelid anatomy (5)
- Haired skin
- Tarsal Plate
- Meibomian glands
- Muscle (orbicularis oculi)
- Conjunctiva
Eyelid functions (5)
- Protect the globe
- Clean and lubricate
- Distribute tear film
- Move fluid into NLD
- Remove debris/foreign bodies
What to look for eyelid eval (7)
- Symmetry
- Margin position, integrity
- Swelling
- Wounds, ulcerations
- Condition of glands
- Position of lashes
- Effectiveness of blink mech
Most common eyelid dz etiology (2)
- Trauma
2. Neoplasia
Modified Hotz-Celsus
surgical repair intropion take out half moon shape of bottom lid
H-plasty
Surgical technique to remove part of bottom eyelid
Beta radiation and strontium radiation
Don’t penetrate eyelid well, but good for cornea
Intralesional chemotherapy (5)
- Series of 8+ injections cisplatin maybes
- Worse before better
- Best as adjunct
- Continue injections until clean bx
- Remission up to 1 yr….
PDT (4)
Photodynamic Therapy
- photosensitizing agent and light in presence of oxygen to produce a localized phototoxic effect
- Reactive oxygen species formed
- Cytotoxicity via-apoptosis, necrosis, autophagy associated cell death
- Infuse agent into affected tissue-apply light source
Sarcoid immunotherapy (4)
- BCG (Bacillus-Calmette-Gaerin
- Series intralesional injections
- Worse before better
- Small risk anaphylaxis
DIstichiasis
Eyelash emerges from meibomian gland
Trichiasis
Eyelashes grow towards the eyeball
Ectopic cilia
hair in a place it shouldna be
Behavoir of SCC
Locally aggressive
-treat early and aggressively
SCC Treatment options (10)
- Surgical excision
- Radiation
- Cryotherapy
- Intralesional chemotherapy
- Intralesional chemotherapy
- Photodynamic therapy (PDT)
- Immunotherapy (BCG)
- Hyperthermia
- Laser ablation
- Combo therapy
Gold standard for many eyelid neoplasms
Radiation
Sarcoid treatment options (9)
- Benign neglect
- Radiation
- Immunotherapy
- Photodynamic therapy (PDT)
- Surgical excision
- Cryotherapy
- Intralesional, topical chemotherapy
- Hyperthermia
- Combo