Dz of Equine cornea Flashcards
1
Q
Functions of cornea (4)
A
- Anterior structure for globe
- Protection interior structures
- Refraction
- being clear
2
Q
Corneal clarity (3)
A
- Avascular
- Anhydrous
- Regular arrangement of collagen fibers
3
Q
Pigment (4)
A
- Usually secondary to chronic irritation
- Pigment migrates from limbus
- Ush in superficial cornea
- Frequently develops in assoc with conjunctival flaps
4
Q
Edema from (3)
A
- Fluid leaking in from tear film
- Leaky blood vessels
- Innefective pumping out by endothelium
5
Q
Mineralization
A
- Usually dystrophic
- Rarely metastatic
- Corneal dystrophies, band keratopathies, ERU, Topical steroids
6
Q
Stem cells located
A
at limbus
7
Q
Epithelium migration
A
0.6-1.0 mm/day if healthy
8
Q
Time for epithelial cell basement membrane to attach to stroma
A
6 weeks
9
Q
Basal cells must adhere to
A
Basement membrane for healing
10
Q
If basement membrane injured healing
A
may be prolonged (weeks to months)
11
Q
Indolent ulcers may have
A
basement membrane abnormality
12
Q
Stroma healing (4)
A
- PMNs appear around necrosis
- Cells adjacent to wound ege transform-accumulation fibroblasts
- Bibroblasts proliferate and make collagen
- COllagen fibrils are disorganized, makes opaque spots
13
Q
Endothelium healing (2)
A
- Minimal to no mitosis
2. when cells lost, remaining cells inlarge and migrate
14
Q
Superficial ulcer means
A
only epithelium is lost
15
Q
Suspect fungal ulcers if (4)
A
- It doesn’t heal quickly
- Does not vascularize
- Is associated plant/organic debris
- Has been treated with corticosteroids
