equine antimicrobials Flashcards

1
Q

What are the TEN classess of antimicrobials available for use in equids

A
  1. beta lactams
  2. cephalosporins
  3. aminoglycosides
  4. chloramphenicol
  5. potentiated sulphonamides
  6. tetracyclines
  7. fluroquinolones
  8. macrolides
  9. rifampin
  10. metronidazole
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2
Q

which of these are bacteriostatic

A

macrolides
potentiated sulphonamides
tetracyclines
chloramphenicol

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3
Q

which are bacteriocidal

A

penecillin
fluroquinolones
cephalosporins
metronidzole

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4
Q

what cephalosporin used in practice and what is its importance

A

ceftiofur
high importance

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5
Q

which aminoglycoside is used and what is its importance

A

gentamycin
medium importance

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6
Q

which potentiated sulphonamide is used and whats it importance

A

TMPS
low importance

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7
Q

which macrolides are used and whats their importance.
why should only foals be given it

A

erythromycin
low importance

only use in foals with rhodococcus equi. cause severe colitis in adult horses

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8
Q

what is commonly given to foals with rhodococcus equi

A

erythromycin + rifampin

(These two are ONLY used to treat rhodococcus, nothing else)

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9
Q

what is a fluroquinolone thats used and whats its importance

A

enrofloxacin
high importance

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10
Q

what is metronidazole used for and whats its importance

A

commonly given with penecillin and gentamycin for broad spectrum cover including anaerobes

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11
Q

why should care be taken with chloramphenicol

A

not to be used in animals entering food chain.

dont given concurrently with penecillin, gentamycin, fluroquinolones or macrolides

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12
Q

which antibiotics are prohibited if entering the food chain

A

gentamycin, chloramphenicol, metronidazole

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13
Q

what microbial should be used if horse given A2 agonist

A

TMPS
causes fatal dysrhythmia

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14
Q

what condition in foals can tetracycline be used for

A

contracted tendons

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15
Q

why should fluoroquinolones be avoided in young/growing animals

A

causes cartilage lesions

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16
Q

which antimicrobial is broad spectrum and effective against gram positives

A

beta lactams

17
Q

not many antimicrobials have good efficiancy against anaerobes. Which ones do

A

metronidazole (excellent anaerobic activity)
tetracyclines

18
Q

which three antimicrobials can be given together to cover for all bacteria

A

penecillin (kills g +s)
gentamycin (kills g -s)l
metronidazole (kills anaerobes)

19
Q

what is one drawback of gentamycin

A

nephrotoxic