Equations/Values- Exam 3 Flashcards

1
Q

Filtration Fraction

A

GFR/RBF

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2
Q

Filtration

A

GFR x [Plasma]

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3
Q

Excretion

A

Filtration - Reabsorption + Secretion

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4
Q

Plasma Osmolarity

A

(2.1) x (Plasma sodium concentration)

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5
Q

What percent of PAH in RBF is removed?

A

90%

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6
Q

Net force for reabsorption

A

10 mmHg

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7
Q

Pc

A

13 mmHg

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8
Q

“Pi”c

A

32 mmHg

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9
Q

Pif

A

6 mmHg

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10
Q

“Pi”if

A

15 mmHg

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11
Q

Normal reabsorption rate

A

124 mls/min

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12
Q

Filtration coefficient

A

Reabsorption rate/ Net force

constant under most conditions

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13
Q

ADH MOA

A

V2 receptors, increases cAMP, activates protein kinases, moves aquaporin-2

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14
Q

Chronic Increased ADH

A

Stimulates formation of aquaporin-2 molecules

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15
Q

Low SNS stimulation

A

alpha-receptors on epithelial cells
decreses sodium/water excretion
Stimulates renin -> Angiotensin II

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16
Q

Clearance equation

A
Cs = Us x V / Ps
Us= urine solute concentartion
v= urine flow
Ps = plasma solute concentration

Also, Urinary Excretion/Plasma concentration

17
Q

Urinary Excretion

A

Us x V

18
Q

How to estimate GFR? (if freely filtered)

A

= to urinary excretion

19
Q

What does a 4 fold increase in creatinine mean?

A

GFR is 1/4 normal

20
Q

How to estimate RPF (if freely filtered?

A

= Cs

21
Q

How to calculate RPF from PAH clearance?

A

PAH Clearance/ 0.9

22
Q

Total Blood Flow equation

A

Plasma Flow / (1-HCT)

23
Q

Acidosis causes what to K+ secretion?

A

Decreases K+ secretion

inhibits Na/K pump

24
Q

Prolonged acidosis causes what to K+ secretion?

A

Increases K+ secretion

Decreased sodium reabsorption, increased tubular flow

25
Q

Salt H20 g/mol

A

58.5

26
Q

Inuline estimates what

A

Water absoprtion

27
Q

Inulin of 3 means what

A

1/3 in tubule

28
Q

Absorption

A

Filtered Load- Excretion

29
Q

Secretion

A

Excretion - Filtered load