equations and blood pressure flow Flashcards
preload, contractibility, and after load govern _____ _____
stroke volume
increase preload and contractility _____ stroke volume
increased after load _____ stroke volume
increases
decreases
what is the amount o tension in the ventricular myocardium before it begins to contract
preload
increased preload means ____ force of contraction
increased
exercise _____ venous return and _____ myocardium
cadiomyocytes generate ____ tension during contraction
_____ cardiac output matches venous return
this relates to:
increases, stretches
more
increased
PRELOAD
stroke volume is proportional to the ____ ____ ____
end diastolic volume
ventricles eject blood as much as they receive, so the more they are _____, the harder they _____
stretched
contract
what relates to the length tension relationship of striated muscle
stroke volume proportional to end diastolic volume
what is the optimum resting length in micrometers of cardiac muscle
2-2.5
what is how hard the myocardium contracts for a given preload
contractility
positive inotropic agents raise ____ to increase contractility
what blood disorder can cause strong prolonged contractions and even cardiac arrest in systole
calcium
hypercalcemia
negative ionotropic agents reduce contractility via lowering _____
as well as
raising _____, how does this lower it
lowering ____, how does this lower it
calcium
potassium; prevents depolarization
potassium; hyper polarization
what is the sun of all forces opposing ejection of blood from ventricles
afterload
what is the largest afterload force
it opposes opening of _____ valves
limits ____ ___
blood pressure
semilunar
stroke volume
what condition can increase afterload and oppose ventricular ejection
what is the bigger picture around afterload and diseases
hypertension
anything that impedes arterial circulation can increase afterload
the _____ nervous system raises HR,
sympathetic
chronotropic:
inotropic:
heart rate
stroke volume
what is the amount ejected by each ventricle in 1 min
cardiac output
regular cardiac output for: (L/min)
rest
fit person during exercise
world class athlete
5
21
40+
what is the difference between a persons maximum and resting cardiac output
cardiac reserve
cardiac reserve ____ with fitness, and ____ with disease
increases
decreases
cardiac output = ____ x ____
heart rate
stroke volume
what 4 things do capillaries pass between blood and tissue fluid
gasses
nutrients
wastes
hormones
what 5 things are capillaries scarce in
tendons
ligaments
epithelia
cornea
lense
what type of capillaries are in most tissues and organs
their endothelial cells have ____ junctions
they form a continuous tube with ____ ___ that allow passage of solutes such as glucose
____ wrap around capillaries and contain the same contractile protein as muscle so that they can ____ and regulate blood flow
continuous
tight
intercellular clefts
pericytes, contract