cardiac muscle and conduction system Flashcards

1
Q

are cardiomyocytes striated

in them, there is one central ___ surrounded by a light staining mass of _____

A

yes

nucleus, glycogen

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2
Q

what join myocytes together

what interlock and increase the area of contact between cells on them

A

intercalated discs

interdigitating folds

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3
Q

in relation to mechanical junctions on intercalated discs:

what are actin that are anchored to the plasma membrane

what are they linked via

what do desmosomes do

A

fascia adherens

transmembrane proteins

punctate

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4
Q

in relation to electrical junctions: (gap junctions) ____ flow between cells, allows entire myocardium of either ____ atria or ventricles to act like a _____ unified cell

A

ions

two, single

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5
Q

cardiac muscle depends almost exclusively on ____ ____ to make ATP

what two molecules are rich in myocytes

what fills 25% of the cell

A

aerobic respiration

myoglobin and glycogen

mitochondria

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6
Q

myocardia are adaptable to different organic fuels, what percentage correspond to the following:

fatty acids
glucose
amino acids

what two other things is it adaptable to

A

60%
35%
5%

ketones, lactate

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7
Q

the heart is fatigue resistant because it makes little use of _____ ____ or _____ debt mechanisms

A

anaerobic fermentation

oxygen debt

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8
Q

what percent of the heart is made of nodes

what are they essentially

A

1%

modified myocytes

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9
Q

what node is considered the pacemaker

A

SA node

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10
Q

conduction system in words:

____ node fires
excitation spreads through _____ myocardium
____ node fires
______ conducting networks distributes excitation through ventricular myocardium (down and up)

A

SA
atrial
AV
purkinje

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11
Q
A
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12
Q

what is the normal heartbeat triggered by SA node

A

sinus rhythm

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13
Q

an adult at rests HR:
adult HR without vagal tone:
what nervous system deal with vagal tone

A

70-80 bpm
100 bpm
autonomic

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14
Q

what is a region of spontaneous firing other than the SA node

A

ectopic focus

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15
Q

what is the heart rate if there is an ectopic focus on the AV node

A

40-50 bpm

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16
Q

what is the threshold for resting potential

A

-40 mV

17
Q

the SA node stimulates two ___ to contract almost simultaneously
how many ms does this take

where does the signal slow down through
how much does it delay the signal

A

atria
50

AV node
100 ms

18
Q

the signals travel very ____ through AV bundle and subendocardial conducting network

A

quickly

19
Q

what is another term for purkinje fibers

A

sunendocardial conducting network

20
Q

ventricular systole progresses ___ the apex

A

up

21
Q

what is a composite of all action potentials of nodal and myocardial cells detected

remember, it is a recording of ALL _____, not just nodes

A

ECG
myocardial

22
Q

deviations of ECG from normal can indicate:
myocardial ____
abnormalities in _______ pathways
heart ______
______ and _____ inbalances

A

infarction
conductions
enlargement
electrolyte, hormone

23
Q

what is endothelia in blood vessels

A

tunica interna

24
Q

where is the smooth muscle, collagen, and elastic tissue in blood vessels

A

tunica media

25
Q

where is the connective tissue in blood vessels

A

tunica externa

26
Q

what are at the boarder between interna and media

A

internal elastic lamina

27
Q

what are at the boarder between media and external

A

external elastic lamina

28
Q

the elastic lamina:

_____ during systole
what does this do

_____ during diastole
what does this do

A

expand
take pressure off smaller downstream vessels

recoil
maintains pressure during relaxation and keep blood flowing

29
Q
A