EQ Laminitis Flashcards
Define laminitis
Disintegration of the laminar attachments due to loss of laminin and collagen from the basement membrane
Describe the enzymatic theory of laminitis
Imbalance of MMPs and TIMPs
What trigger factors can predispose to laminitis?
G-ve endotoxin G+ve exotoxin - carb overload Strep bovis exotoxin Colic - carb overload Colitis Pleuropneumonia RFM Vasodilation
What endocrine clinical situation can lead to laminitis?
Hyperinsulinaemia/ insulin resistance
What gross pathological signs are seen with laminitis?
Altered angle between P3 and the dorsal hoof wall
What radiographic signs are seen with laminitis?
Gas shadow
Altered P3 angle
Altered sole depth
What clinical signs are seen with laminitis?
Acute lameness - worse on hard/ circle Digi pulses Rocked back stance Dropped sole Depression around coronet band Abscessation/ bruising Recumbent
What is the founder difference?
Distance between the extensor process of P3 and the proximal dorsal hoof wall
Describe the basic principles of laminitis treatment
1) Treaet primary disease
2) Pain relief - bute/ flunixin - NSAIDs are good as they are also anti-endotoxaemics
3) Digital supports - bedding/ fitted supports
4) Others - cryotherapy/ vasodilation therapy
When would it not be wise to use ACP in treatment of laminitis?
The developmental phase - don’t want more trigger factors getting to foot!
When would a poor prognosis for laminitis be assumed?
> 15 degrees of P3 rotation
Distal P3 displacement
P3 solar prolapse
Founder
What sequelae may be seen with chronic laminitis?
Seedy toe Dropped sole Foot abscess Altered hoof growth DDFT tension
