EQ Breed Dispositions Flashcards
RER
Thoroughbreds
Give Dantrolene before exercise
PSSM
QH
Dominant
Type 1: drafts (Belgians, percherons), halter horses (QHs, appaloosas, paints) GYS1 mutation
Type 2: performance horses (QH, warmbloods)
CK exercise trial
HYPP
QH and halter horses
Dominant
ATPase channel doesn’t work —> hyperkalemia (give dextrose)
MH
QH and pigs and humans
Dominant
Ryanodine receptor mutation
Triggered by anesthesia, succinylcholine, and stress
Give Dantrolene
HERDA (Hereditary Equine Regional Dermal Asthenja Disorder)
QH
Recessive
Defective collagen (skin sloughs)
GBED
QH, paints, appaloosas
Recessive
FATAL
Muscle weakness, repro issues
IMM
QH, reining, working cow horses, halter horses
Strangles causes it
Mutation in myosin heavy chain 1 (MYH1)
Immune system targets muscles on topline and gluteals
Calciphylaxis (fatal)
Myofibrillar myopathy
Arabians and warmbloods
Muscle stiffness (mild signs of RER but no elevated muscle enzymes)
Linked with previous PSSM 2 diagnosis
Stain for Desmin on muscle biopsy
ERU
Appaloosas
Autoimmune so give steroids (or cyclosporine implant)
Night blindness
Leopard appaloosas and Tennessee walkers
Incomplete dominance
Can test genetically
Multiple congenital ocular anomalies (MCOA)
Rocky Mountain horse (silver coats)
Cysts, big cornea, weird iris and retina
Lethal white ovaro
2 frame ovaros
Incomplete dominance
Blue eyes and deafness
Splashed paints (white face)
Endothelium B receptor mutation
Warmblood fragile foal syndrome
Warmbloods
Connective tissue defect that’s fatal (hyperextensible)
Recessive
Red foot dz and junctional epidermolysis bullosa
Belgians and American Saddlebreds
Blistering of skin and mouth, hooves slough
Recessive
Lavender goal syndrome
Arabians
CNS signs and hyper extension- fatal
Recessive
Juvenile idiopathic epilepsy
Egyptian Arabian goals
Seizures that stop after 1yo
Cerebellar abiotrophy
Arabians
Neuro signs that show up by 6mo (normal at birth)
Don’t ride (pasture pet)
Recessive
Severe Combined Immunodeficiency (SCID)
Arabians
No immune system- fatal
Recessive
Strangulating lipomas
Arabians and old
fecaliths
Minis
EMS
Ponies, Arabians, donkeys, minis, Morgan’s, Paso Finos, Fjords, gaited horses (TN walking horse, Missouri fox trotters, saddlebreds)
Fat middle aged
Laminitis
PPID
No breed association, just old
Navicular dz
QH, TB, WB
4-15yo