Epithelium HY Flashcards

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1
Q

Where is simple squamous epithelium found?

A

Pericardium, Pleura, and Peritoneum

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2
Q

Where is pseudostratified columnar epithelium found?

A

Trachea

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3
Q

Where is non-keratinized stratified squamous found?

A

Esophagus, oral mucose, anal cavity, vagina, cervix

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4
Q

What could a dysfunction in E-Cadherin lead to?

A

Malignant carcinoma & adenocarcinoma

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5
Q

What are the components of desmosomes (macula adherens)?

A

Desmoplakins, plakoglobins, keratin, transmembranous proteins (desmocollins & desmogleins)

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6
Q

What molecules found in gap junctions (zonula communicans)?

A

6 connexins; also found in cardiac and smooth muscle cells

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7
Q

What are the components of the hemidesmosomes?

A

Integrein, perlecan, fibronectin, laminin, collagen type IV, VII, XVII

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8
Q

What is the defect in Bullous Pemphigoid?

A

Auto-Ab against hemidesmosomes

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9
Q

How is Basal Lamina visualized?

A

EM

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10
Q

What is the role of Basal Lamina?

A

Serve as regeneration guide for epithelial, muscle, adipose, schwann cells using CAM and Integrins.

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11
Q

How is Basement Membrane visualized?

A

PAS +ve

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12
Q

What are components of the reticular lamina where the basement attaches?

A

Collagen Type I, III, and VII

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13
Q

Microvilli characteristics?

A

Wheat field; ~1 um, LM: found in brush border of intestine; TEM: axial bundle>20 actin filaments; glycocalyx (furry coat)=PAS +ve

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14
Q

Stereocilum characteristics?

A

Cactus; 8-15um; found male repro & inner ear epithelium

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15
Q

Cilium characteristics?

A

7-10 um; axoneme of MT (9+1 axial doublets); found in endometrium, vas efferens, gametes, resp. epithelium; Primary cilium=immotile (sensory organs); Nodal cilium=motile (gastrulation)

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16
Q

What is the defect and sx of Kartegener syndrome?

A

Defect in dynein arms therefore leading to defects in mucous movements & flagellum leading to chronic resp infections and infertility

17
Q

These glands lose their connections with surface epithelium from which they derived?

A

Endocrine glands

18
Q

These glands maintain their connections with surface?

A

Exocrine glands

19
Q

Tubuloacinar glands examples?

A

Pancreas exocrine, submandibular & sublingual salivary

20
Q

Tubuloalveolar glands examples?

A

Prostatic glands, mammary glands

21
Q

Simple tubular glands examples?

A

Intestinal glands

22
Q

Simple branched tubular glands examples?

A

Stomach glands

23
Q

Simple coild tubular glands examples?

A

Sweat glands

24
Q

Simple branched acinar glands examples?

A

Some urethral glands

25
Q

Compound tubular glands examples?

A

Duodenal glands

26
Q

Compound acinar glands examples?

A

Pancreas exocrine

27
Q

Comoound tubuloacinar glands examples?

A

Some salivary glands

28
Q

Sublingual salivary gland features?

A

Mucous acinus (protein)

29
Q

Parotid gland features?

A

Serous acinus

30
Q

Demilune secretion?

A

Mixed serous and mucous when demilunes are present