Epithelium & Glands Flashcards
Type of epithelium found in the lining of the blood vessels, plueral cavity, peritoneum, and pericardium.
Simple squamous epithelium
Give example of simple cuboidal epithelium
Thyroid and ovarian follicle
Where does simple columnar epithelium usually found
Intestine, renal collecting tubules
Cell shape that is tall as they are wide. With spherical nucleus.
Cuboidal
Elongated cell shape with elongated nucleus
Columnar
Type of epithelium that shows an illusion of stratification.
Pseudostratified epithelium
Where is stratified squamous Keratinized epithelium found?
Epithelia
Where is stratified squamous non keratinized epithelia found?
Mouth, vagina, anal canal, larynx, esophagus
Where is pseudostratified found?
Nasal cavity, bronchi, trachea
Where is stratified columnar epithelium found?
Conjunctiva
Aggregated polyhedral cells
Epithelia
Characteristics of epithelium
Avascular
Polarity
Presence of basement membrane or basal lamina
Presence of cell juntion
Main intermediate filament of epithelia
Keratin
Is keratin made of dead skin cells?
T
Diff. Basal lamina with basement membrane.
Basal lamina is a part of basement membrane
2 parts of basement membrane
Basal lamina
Reticular lamina
What type of collagen is basal lamina made of?
Type IV collagen
What type of collagen is reticular lamina made of?
Type III collagen
What binds basal and reticular lamina?
Type VII collagen
Enumerate the Junctions of epithelium
Tight junction Adherens Desmosomes Hemidesmosomes Gap junction
Tight junction (zonula occludins)
Protein component
Function
Defect
Occludin & claudin
Ensure that mol travel transcellularly and not paracelullarly
Compromised BBB. Neurological disorder.
Zonula adherens / adherent junction
Protein component
Function
Defect
E-cadherin & catenin
Terminal Web
Carcinoma
Desmosomes (Macula adherens)
Protein component
Function
Defect
Cadherin family
Strong achor
Skin disorder
Hemidesmosomes
Protein component
Function
Defect
Integrin
Binds the epithelium to the basal lamina
Epidermolysis bullosa (blisters)