Epithelium 1 Flashcards
Characteristics of the epithelial cells
- Composed of closely aggregated cels forming cellular sheets 2. Shapes: squamous, cuboidal, columnar
- Adjacent epithelial cells are adhering by cellular junctions
4.the basal surface rests on the basement membrane
5.avascular - Receive nutrients from connective tissues
7.lamina propria: lines the respiratory and urinary systems - Show polarity (basal and apical poles)
- Papillae projected from connective tissue
- Originate from embryonic layers
- Have nerve fibers
Principal function of the epithelial tissues
- Protection: epidermis
- Absorption: intestinal lining
3.secretions: glands - Contractile: myoepithelium
- Sensory: taste buds
What is the basement membrane?
Its a thin extra cellular sheet of macromolecules between the basal surface of the epithelia and the underlying connective tissue
What is the structure of the basement membrane?
Thin layer
Can be stained with PAS and silver
Secreted from the epithelial cells
Basement membrane structure with the EM
- Cell coat of the epithelial cells (appears as a light zone underneath the outer lamina of the plasma membrane
- Basement membrane proper
- Connective tissue rich in reticular fibers
What is the basal lamina chemically composed of?
Glycoproteins and collagen
(PAS+ve when seen in the LM)
What is the cell coat?
Oligosaccharide chains linked to lipid and protein molecules and extended outward from the plasma membrane forming the cells glycocalyx (cell coat)
Functions of the basement membrane
1.Provides structural support for the epithelial cells
2.acts as a filter of diffusing macromolecule (kidney)
3. Maintains cell polarity
4. Permits the flow of nutrients
5. Controls epithelial growth and differentiation