Epithelial Tissue Flashcards
What is the general structure of epithelial tissues?
- 1 layer or more of tightly packed cells, with exposed apical surface and cells attached to the basal membrane (like a carpet)
What is the general function of epithelial cells?
- lines surfaces to protect
- forms glands to secrete
What are the 4 characteristics of E tissue?
1) cells have polarity
2) layers of tightly packed cells bound together by cell junctions
3) avascular
4) high rate of cell division to replace lost/damaged cells
What are the characteristics of E cells?
- apical surface is exposed
- unequal distribution of organelles
- basal surface anchored to underlying connective tissues
Why can skin shed off?
- the apical skin has older dead cells which can be rubbed off
Why doesn’t skin come off when pulled?
-basal surface of skin Is connected to underlying tissue
What is underneath the basal surface?
-protein filaments made by epithelial tissue and underlying connective tissue
What are tight junctions?
- interlocking membrane proteins fuse adjacent cell membranes
- prevents molecules moving between cells
eg. need acidity from eating away at stomach and other tissues
What are desmosomes?
- transmembrane proteins reinforced by cytoskeleton
- strong connections resists stretching, twisting
eg. when you burn the top of your mouth –> skin comes off in “sheets”
What are gap junctions?
- channel proteins (connexions) connect cells
- allows for exchange of small molecules, ions
eg. to coordinate cilia beating upward trachea to keep things out of lungs
What does avascular mean?
- no blood vessels present –> never any capillaries or. veins in tissue itself
- exchange of nutrients, waste by diffusion
Why is it important for E tissue to have high rates of cell division? Why is this a downfall?
eg. why your skin cells can rejuvenate
- bad because chemotherapy targets cancerous cells that are dividing quickly but will also kills healthy E cells also travelling quickly
What is the structure of simple squamous epithelial tissue?
-one layer of flat cells = thin and fragile
What is the function of simple squamous E tissue?
-lines protected areas that are not exposed to the outside world
Where are simple squamous E tissue found?
- mesothelium lines body cavities
- endothelium lines heart, blood vessels
- walls of alveoli and capillary for gas exchange