Epithelial Tissue Flashcards
Epithelial Tissue
Covers exposed surfaces, lines internal passageways or forms glads.
May be derived from each of the three embryologic germ layers.
Characteristics
- Cellularity
- Polarity
- Attachments
- Avascularity
- Regeneration
Cellularity
Cells packaged tightly together.
- Intercellular Cement
- Cell Adhesions Molecules
- Cell Junctions
Intercellular Cement
Made from sticky proteoglycans containing glycosamines
Cell Adhesion Molecules (CAM’s)
Transmembraneous proteins that proceed through the cell membrane and can bind to CAM’s from other cells or to the basal lamina.
Cell Junctions
Specialized areas to bound or interlocking membranes.
- Tight Junctions
- Gap Junctions
- Desmosomes
Tight Junctions
Band of transmembrane proteins which produce a waterproof barrier.
Gap Junctions
Allow substances like ions to freely flow from one cell to another.
Desmosomes
Patches of plaques reinforced by intermediate filaments .
They are found in areas subject to much mechanical stress.
Polarity
There is an apical portion on top and a base below (above loose CT)
Attachments
Hemidesmosomes attach epithelia to basement membrane
From epithelia secretions from above lamina lucida and lamina densa from CT secretions from below
Avascularity
Derive nutrients from absorption through basement membrane
Regeneration
Often subject to mechanical stress, damage and cell loss
Stem cells (also known as germinative cells) are often located near the basement membrane.
Function
- Physical Barrier
- Selective Permeability
- Provide Sensation
- Specialized Secretion
Physical Barrier
Serves as lining or covering to server as barrier