Epithelia and Glands Flashcards

1
Q

What are the four tissue types

A
  • Epithelia
  • Muscle
  • Connective tissue
  • Nerve
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2
Q

What are epithelia

A

Closely appose sheets of cells

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3
Q

What are the three primary germ layers

A
  • ectoderm
  • mesoderm
  • endoderm
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4
Q

What does the ectoderm form

A

epidermis

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5
Q

What does the mesoderm form? And what does this line?

A

mesothelium (lines the pericardium, pleurae and peritoneum)

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6
Q

What does the endoderm form?

A

Lining of the GI tract

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7
Q

Where do we find epithelia? And it’s names

A

Epithelia- on surfaces
Endothelium- lining blood vessels
Mesothelium- lining body cavities

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8
Q

Basic characteristics of epithelia

A
  • Entirely cellular
  • Cell polarity
  • specialised contacts between cells
  • Lateral communication between cells
  • basal lamina (basement membrane) separating from underlying tissue
  • Call replacement, often rapid turnover
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9
Q

How are epithelia classified

A
  • Number of cell layers
  • Shape of cells in outermost layer
  • Position of nuclei
  • Transitional
  • Ciliated
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10
Q

How can the number of cell layers be categorized?

A
  • simple

- compound or stratified

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11
Q

How are shapes of cells in outermost layer categorized?

A
  • squamous (flat)
  • cuboidal
  • columnar (longer than wide)
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12
Q

How can position of nuclei be categorized?

A
  • Stratified

- pseudostratified (different nuclei position)

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13
Q

What is compound/stratified epithelia

A

More than one layer

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14
Q

What is transitional epithelia

A

Shape of cells changes according to need

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15
Q

What’s the function of simple epithelia

A

Absorption

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16
Q

Function of stratified epithelia

A

Protective

17
Q

What are other functions of epithelia

A
  • secretion
  • sensory perception
  • Movement of materials
  • Wound repair
18
Q
  • Where are microvilli found
  • Where are they anchored
  • What do they do
A
  • Apical plasma membrane
  • In terminal web
  • Increase surface area
19
Q
  • Where are cilia found

- What do they do

A
  • apical surface

- Transport materials across surface

20
Q

What sort of core do stereocilia have

A

Microfilament core- modified microvilli

21
Q

What do basal infoldings do

A

Increase surface area

22
Q

What are glands derived from

23
Q

What are the two types of glands

A

Endocrine

Exocrine

24
Q

How are glands formed

A

1) Cells from surface epithelium grow down into underlying tissue (called epithelial cord or tubule)
2) Then either endocrine or exocrine glands form

25
What are exocrine glands
The connecting cells persist to form duct and the deepest cells become secretory
26
What are endocrine glands
Connecting cells disappear and the deepest checks remain to secrete into capillaries
27
Types of exocrine ducts
Eccrine Holocrine Apocrine
28
What do eccrine glands do
Involve exocytosis with no loss of cells (e.g. salivary glands)
29
What do holocrine glands do
Loss of whole cel during secretion (e.g. sebaceous glands)
30
What do apocrine glands do
Loss of apical surface of cells as membrane bounded vesicles (e.g. sweat glands)
31
What do endocrine glands do
Secrete directly into blood stream
32
What is the importance of the basement membrane
It is a boundary between epithelia, muscle, and nerve and connective tissue -it is important to control the spread of disease and infection
33
What links basement membrane to sheet of epithelial cells
Hemidesmosomes
34
What does the basement membrane consist of
- Basal lamina | - Reticular fibres
35
What is the basement membrane said to be in relation to the ECM
condensed layer of ECM
36
Why is basement membrane and the basal lamina considered to be a molecular sieve?
Impenetrable barrier but permits the flow of nutrients and metabolites
37
Constituents of basement membrane and basal lamina
- heparan sulphate - collagen type 4 - fibronectin - laminin - entactin - perlecan
38
What do laminin and type 4 collagen attach to
hemidesmosomes and integrin receptors
39
What do cancer cells need to cross the basal lamina
- Type 4 collegenase | - Laminin receptors