Episode 7 Blood Groups Flashcards

1
Q

How many different blood group systems are there? How many antigens within these systems?

A

30 blood group systems

600+ antigens

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2
Q

In what manner are genes for ABO inherited?

A

Mendelian manner

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3
Q

What is the ABO system based on?

A

Sugar based, rather than protein based. Based on type of carbs you have in the membrane of your RBCs

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4
Q

What are the four major blood groups?

A

A, B, AB, O

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5
Q

Group A has what type of antibodies? Group B?

A

A has Anti-B; B has anti-A. They are antagonistic to each to each other

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6
Q

What antibodies does group AB have? Group O?

A

AB - NO antibodies; O has both anti-A and anti-B

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7
Q

What antigens does each blood type have?

A

Each blood group corresponds to the SAME letter antigen as the group name - A has A antigen, B has B antigen, AB has both A and B antigens, and O has NONE

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8
Q

What blood types found in the united states from most to least common?

A

O+, A+, B+, O-, A-, AB+, B-, AB-

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9
Q

What is the universal recipient? Why?

A

AB+ has no antibodies

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10
Q

What is the universal donor? Why?

A

O- has no antigens

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11
Q

Why are you concerned more about the recipients antibodies rather than the donor’s?

A

There is much more recipient blood already in the their body than the donor amount

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12
Q

Why are you not concerned about donating type O to type AB, if O has both A and B antibodies?

A

The volume of donated O blood is too diluted in the recipients blood to cause any harm. The recipients blood AB does not have any antibodies so it will not attach type O

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13
Q

How many Rh antigens are out there?

A

around 50

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14
Q

How many common Rh antigens are there? what are they called?

A

Five - D, C, c, E, e

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15
Q

Which Rh antigen is most common?

A

D

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16
Q

Which antigens does an O+ blood type have?

A

Rh antigen, but no A or B

17
Q

Which antigen does an A+ person have?

A

A antigen and Rh antigen

18
Q

What antigen does O- have? A-?

A

O- has no antigens

A- only has A antigen, NO Rh antigen

19
Q

What is a hemolytic transfusion reaction caused by?

A

Incompatible transfusion due to an antigen-antibody reaction, resulting in severe or fatal intravascular hemolysis

20
Q

What is a non-hemolytic transfusion reaction?

A

Due to damaged blood products, high levels of cytokines, leading to fever and chills, usually benign

21
Q

What are five common transfusion reactions to avoid?

A

Hemolytic, Non-hemolytic, Allergic, volume overload, and transfer of bacteria

22
Q

What can blood volume overload lead to?

A

Pulmonary edema

23
Q

What can a transfer of bacteria lead to?

A

Edotoxemia and septicemia; potentially fatal

24
Q

What is Hemolytic Disease of the Newborn (HDN)?

A

Happens when Rh- women are carrying Rh+ babies. However, during birth or miscarriage, placental tearing exposes mother to Rh+ fetal blood. Mother begins to produce anti-Rh agglutinins. If she becomes pregnant again with a second Rh+ positive baby then the baby’s RBC will be attacked by mothers agglutinins and the baby is born with a severe anemia called HDN.