Epileptogenesis Flashcards
1
Q
Traumatic brain injury is due to what mechanism?
A
Reduced GABAergic inhibition inter neurons
2
Q
Increased excitability is related to to what changes?
A
GABAergic inhibition and excitation
3
Q
GABAergic inhibition can be due to what?
A
Loss of inter neurons, alterations of chloride gradients in excitatory cells
4
Q
What can excitation increases be due to?
A
Axonal sprouting that causes aberrant recurrent excitation, loss of afferent inputs
