Epilepsy Flashcards

1
Q

Temporal lobe focal symptoms

A
Automatisms
Abdominal nausea/pain
Dysphasia
Memory phenomena
Emotional disturbance (hippocampal involvement)
Hallucinations (uncal involvement)
Delusions
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2
Q

Fontal lobe focal symptoms

A
Motor features
Jacksonian seizure
Motor arrest
Dysphasia/speech arrest
Post-ictal Todd's palsy
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3
Q

Parietal lobe focal symptoms

A
Sensory disturbance
Motor symptoms (spread to percentile gyrus)
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4
Q

Occipital lobe focal symptoms

A

Visual phenomena

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5
Q

Structural causes of seizure

A
Cortical scarring
SoL
Stroke
Hippocampal sclerosis
Vascular malformation
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6
Q

Developmental abnormalities causing seizure

A

Cortical dysgenesis

Dysembrioplastic neuroepithelial tumour

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7
Q

Metabolic causes of seizure

A
Na disturbance
Hypercalcemia
Glucose disturbance
Uraemia
Liver disease
Drugs (TCAs, cocaine)
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8
Q

3 questions when diagnosing a seizure

A
  1. Was it a seizure?
  2. What kind of seizure?
  3. What are the triggers/causes?
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9
Q

What anti-epileptic drugs do you do blood monitoring for?

A

Phenytoin

Phenobarbital

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10
Q

Anti-convulsant intoxication triad

A

Ataxia
Nystagmus
Dysarthria

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11
Q

When to withdraw anti-epileptic medication

A

After 2 years seizure-free

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12
Q

Treatment for Partial seizure

A
  1. Carbamazepine
  2. Lamotrigine
  3. Valproate
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13
Q

Treatment for absence seizure

A
  1. Valproate

2. Lamotrigine

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14
Q

Treatment for generalised Gran-mal seizure

A
  1. Valproate
  2. Lamotrigine
  3. Carbamazepine/Topiramate
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15
Q

SEs Valproate

A
Appetite and weight gain
Liver failure
Pancreatitis
Reversible hair loss (grows curly)
Oedema
Ataxia
Tremor, thrombocytopenia, Teratogenic
Encephalopathy (hyperammonaemia)
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16
Q

SEs carbamazepine

A
Leucopaenia
Diplopia, blurred vision
Impaired balance, drowsiness
Rash
SIADH
17
Q

SEs Lamotrigine

A
Maculopapular rash (risk Stephen Johnson)
Hypersensitivity
Diplopia
Photosensitivity
Aplastic anaemia
Tremor
Agitation
18
Q

SEs Phenytoin

A
Gum hypertrophy
Nystagmus
SLE
Hirsutism
Depression
19
Q

Management of seizure >3 mins

A

10mg rectal/IV diazepam/lorazepam

20
Q

Management of status epilepticus in community

A

10 mg rectal diazepam/buccal medazolam

21
Q

Management of status epilepticus in hospital

A

4mg IV lorazepam in 2mg/min

Repeat 10 mins later