Epilepsy

Question 1

What treatment is first-line for Tonic-Clonic seizures in women that are pre-menopausal?

Answer 1

Lamotrigine

Question 2

What medication is first-line for generalised tonic-clonic seizure (not including women of childbearing age)?

Answer 2

Sodium Valproate or Carbamazepine

Question 3

What medication may exacerbate myoclonic seizures?

Answer 3

Lamotrigine

Question 4

What medications may exacerbate myoclonic seizures and absence seizures?

Answer 4

Carbamazepine and Oxcabarzepine

Question 5

What list of medications can be used as adjunctive treatments for Tonic-Clonic seizures if monotherapy was ineffective or not tolerated?

Answer 5

Clobazem, levetiracetam, sodium valproate, lamotrigine and topiramate

Question 6

What is first line for absence seizures?

Answer 6

Ethosuximide or Sodium Valproate ( N.B. that taken SV for absence seizures can increase risk of generalised tonic-clonic seizuires).

Question 7

What is an alternative treatment for absence seizures?

Answer 7

Lamotrigine

Question 8

What is first line for myoclonic seizures?

Answer 8

Sodium Valproate

Question 9

What is the alternative treatment for myoclonic seizuires?

Answer 9

Topiramate or Levetiracetam.

Question 10

What is first line for Atonic/Tonic seizures?

Answer 10

Sodium Valproate

Question 11

What is the first line treatment for focal (partial) seizures with and without secondary generalization?

Answer 11

Carbamazepine or Lamotrigine

Question 12

What is an alternative treatment for focal (partial) seizures with and without secondary generalization?

Answer 12

Levetiracetam, sodium valproate, oxcarbazepine