Epilepsia Flashcards

1
Q

**

Fisiología de la epilepsia

A

Aumento de glutamato
disminución de GABA

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2
Q

Tx epilepsia

A
  • Benzodiacepinas
  • Barbitúricos
  • Inhibidor de la recaptura de GABA
  • Inhibidor del metabolismo de GABA
  • Bloqueadores de receptores AMPA
  • Inhibidor SV2A
  • BCC
  • Bloqueadores de canales de sodio
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3
Q

Benzodiacepinas

aumento de la frecuencia de apertura de canales GABAa

A

Lorazepam
Diazepam
Miozepam

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4
Q

Babitúricos

aumento de tiempo de apertira de GABAa

A

Fenobarbital
Pentobarbital

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5
Q

Inhibidor de la recaptura de GABA

A

Tiagabina

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6
Q

Inhibidor metabolismo de GABA

inhibe a la GABA transaminasa

A

Vigabatrina

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7
Q

Bloqueador AMPA

A

Ferbamato

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8
Q

Bloqueador del receptor NMDA

A

Ketamina

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9
Q

Inhibidor SV2A

A

Levatiracetam

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10
Q

BCC

A
  • etosuximida
  • Gabapentina
  • Pregabalina
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11
Q

Bloqueador canales de sodio

A
  • Carbamazepina
  • oxcarbamazepina
  • Fenitoína
  • Fosfenitoina
  • valproato
  • lamotrigina
  • topiramato
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12
Q

Tx crisis de ausencia

A

Etosuximida
Valproato
Lamotrigina

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13
Q

tx crisis convulsivas en nenatos

A

fenobarbital

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14
Q

tx crisis mioclónica

A

Valproato
SV2A

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15
Q

tx crisis tónico-clónicas

A

valproato

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16
Q

tx primera línea convulsiones focales

A

oxcarbazepina

17
Q

En embarazo cuales se pueden usar?

A

Lamotrigina

18
Q

Bloqueadores de canales de sodio que producen sx de steven johnson

A
  • carbamazepina
  • Lamotrigina
19
Q

BCNa hepatotoxicos

A

Carbamazepina
Valproato

20
Q

BCNa teratogénicos

A
  • Fenitoína
  • Fosfenitoína
  • Valproato
21
Q

tx primera línea estatus epileptico

A

benzodiacepinas