Epidural Anesthesia Flashcards

1
Q

what is an epidural anesthetic?

A
  • reversible chemical blockade of neuronal transmission produced by the injection of a local anesthetic into the epidural space to the region of the dural cuffs
  • leaks into intravertebral foramen and prarvertebral spaces
  • medication spread is diffusion dependent
  • onset longer
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2
Q

what does an epidural anesthetic block?

A

-temporary interruption of autonomic, sensory and motor nerve fiber transmission that is dependent on the drug concentration and volume of drug instilled into the space

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3
Q

advantages of epidural anesthesia

A
  • reduces surgical stress
  • reduces overall blood loss (debated in literature)
  • decreases risk of DVT (MOA unknown, but maybe stops stress response and interrupts coagulation cascade)
  • provides anesthesia and/or analgesia –> can re dose with catheter or convert from pain management to primary anesthetic
  • it is versatile –> you can control the extent of the sensory and motor blockade; can be used with adjuncts
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4
Q

disadvantages of epidural anesthesia

A
  • PDPH due to larger needle
  • sympathetic blockade occurs 100% of the time (hypotension, bradycardia)
  • block may last much longer than the procedure
  • urinary retention
  • regional takes “too much time”
  • more difficult than spinal
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5
Q

why would you pick an epidural?

A
  • discuss case with the surgeon, could be part of a multimodal pain management in ERAS
  • management of labor pain
  • procedures involving the abdomen or lower extremities
  • certain comorbidities - pulmonary disease
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6
Q

absolute contraindications to epidural

A
  • patient refusal
  • increased ICP (can cause brainstem herniation)
  • severe aortic or mitral valve stenosis
  • coagulopathy or bleeding diathesis
  • severe hypovolemia
  • infection at the injection site
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7
Q

relative contraindications to epidural

A
  • uncooperative patient (unable to sit still = dangerous)
  • local anesthetic allergy (esters PABA)
  • patient on anticoagulant or thrombolytic therapy (patients with comorbidities like atrial fib or DVT)
  • preexisting neurologic defect
  • chronic HA or backache
  • severe spinal deformity
  • valvular stenosis
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8
Q

patient assessment for epidural anesthesia

A
  • preop does the patient understand the surgical technique
  • explain spinal anesthetic and rational for preference
  • address any patient concerns - fear of being awake or loss of control
  • reassure patient
  • NEVER force or coerce patient into any procedures
  • age considerations
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9
Q

what is involved in informed consent

A
  • advantages and disadvantages
  • block appropriate for procedure but not guaranteed
  • risks and benefits
  • ensure patient understands
  • allow patient to ask questions
  • do not attempt to dissuade from a general if already agreed to
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10
Q

pre-procedure monitoring

A
  • PIV large bore
  • have suction
  • have airway supplies
  • ECG, BP, Pulse ox, oxygen if needed
  • supportive meds - induction agent, paralytic, atropine, vasoactive meds
  • support person ready to stand with the patient the WHOLE time
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11
Q

positions used for epidural

A
  • sitting
  • lateral decubitus
  • prone
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12
Q

neelde approaches for epidural

A
  • midline

- paramedian

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13
Q

placement of epidural

A
  • thoracic - spinous processes form a shield, need steep cephalad angle or paramedian approach
  • lumbar - short, small spinous processes, midline OK
  • caudal - in sacral hiatus; lateral or prone, needle almost parallel to spinal column
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14
Q

patient positioning

A
  • have assistant stand in front of the patient; assistant does NOT leave patients side
  • have patient hold pillow or blanket or lean over a table; drop their head down; roll their back
  • angry cat or shrimp position
  • flexion of the spine will create larger intraspinous spaces and make your procedure more successful
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15
Q

lateral approach patient psition

A
  • maintain midline positioning

- limit spine rotation

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16
Q

what things do you need prior to the start of the procedure?

A
  • patient IV
  • monitoring devices
  • oxygen attached and functioning
  • resuscitation equipment available
  • walk patient through procedure
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17
Q

prepping patient epidural procedure

A
  • ensure proper positioning
  • ensure comfortable for you too
  • palpate landmarks with ungloved hand - iliac crests, spinous processes of lumbar vertebrae
  • use most identifiable interspace (usually L2-3)
  • examine one level above and one level below and if you can’t feel use ultrasound
  • STERILE
  • open tray and inspect integrity of components
  • 3cc - local skin wheal
  • 5cc - local injection
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18
Q

what must you wear for the procedure?

A
  • hat
  • mask
  • sterile gloves
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19
Q

3 cc syringe

A

local skin wheal

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20
Q

5 cc syringe

A

local injection

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21
Q

steps of epidural procedure

A
  • position patient
  • find spot
  • open tray using sterile technique
  • prep patient with CHG or betadine - allow to dry
  • set up tray and draw up medications (be consistent)
  • cleanse site
  • apply sterile drape with your site at the center of the circle
  • straddle selected interspace with middle and index fingers of non-dominant hand
  • raise a small intradermal skin wheal of LA with 25-27G needle (can advance as a guide to feel where you want to go)
  • epidural needle placed with bevel cephalad
  • advanced through - supraspinous, interspinous; advanced mm by mm; SLOW
  • once through ligamentum flavum will feel loss of resistance
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22
Q

epidural needles

A
  • marked in 1 cm increments

- large needles

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23
Q

standard epidural needle size

A

9 cm

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24
Q

touhy needle

A
  • pronounced curve
  • easier for novices
  • directional placement of catheter
  • want bevel up and curve facing caudad so the catheter threads up
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25
Q

crawford needle

A
  • not curve
  • easier to insert
  • BUT higher rate of dural punctures
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26
Q

standard depth to ligamentum flavum at lumbar level

A

5 cm

varies with level and body habitus

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27
Q

bromage grip

A
  • hand firm support to stabilize the needle
  • attach and secure the syringe
  • passing catheter through needles
  • non-dominant hand stabilizes patient’s back
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28
Q

alternate grip

A
  • attach and secure syringe
  • needle placed with bevel cephalad
  • hands to stabilize needle on both sides
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29
Q

loss of resistance method

A
  • most common method
  • glass or plastic syringe
  • fill with 2-3 mL saline with air bubble
  • attach to epidural needle
  • resistance noted while needle is in the various ligaments until epidural space is entered
  • pressure on back of needle; when feel loss of resistance, in the epidural space
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30
Q

hanging drop method

A
  • hub of epidural needle filled with saline until small drop visible
  • negative pressure created as needle passes into epidural spaces SUCKS drop in
  • more pronounced at thoracic levels
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31
Q

dilation of epidural space

A
  • once needle passes through the epidural space, immediate loss of resistance is noted
  • contents of syringe injected into space
  • when syringe is removed, common to see a small amount of clear fluid
  • puncture of dura will result in LARGE amt of CSF
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32
Q

epidural catheters

A
  • typically 2 gauges smaller than needle
  • open-ended
  • multiport - lower incidence of inadequate analgesia; higher incidence of accidental vein cannulation
  • markings help to identify depth of catheter placement
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33
Q

dashed lines

A

1 cm

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34
Q

two dashed lines

A

10 cm

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35
Q

thick line

A

12 cm

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36
Q

catheter placement

A
  • when thick black mark is flush with hub, catheter is flush with needle tip
  • slight resistance noted when catheter is advanced
  • if catheter has a stylet, retract prior to advancing
  • inform patient of possible paresthesia (if one occurs STOP)
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37
Q

how far do you advance the epidural catheter?

A

3-5 cm past the needle hub

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38
Q

shallow placement

A

can get dislodged from epidural space

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39
Q

deep placement

A
  • puncture of dura
  • passage into epidural vein
  • migration through intervertebral foramen
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40
Q

remove needle

A
  • slowly withdraw needle over catheter
  • once needle is removed, note the depth of the catheter at the skin
  • if depth is less than 1 cm to the epidural space REPLACE
  • never attempt to withdraw the catheter through the needle
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41
Q

test dose

A
  • 1.5% lidocaine with epinephrine 1:200,000
  • 15 mg/mL lidocaine and 5 mcg/mL epi
  • inject 3 mL –> 45 mg lidocaine and 15 mcg epi
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42
Q

subarachnoid placement

A

spinal - hypotension brady

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43
Q

intravascular placement

A

greater than 20% increase in HR and BP

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44
Q

secure catheter

A
  • looped and taped away from midline
  • minimizes chance of dislodgement
  • keep OFF spinous processes
  • placed over shoulder
  • secure label to end of catheter!!
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45
Q

paramedian approach

A
  • useful when patient cannot flex spine (history of previous spine surgery, RA, or hip/upper leg trauma)
  • skin wheal 1 cm lateral and 1 cm caudal to spinous process
  • advance needle toward midline
  • needle passes through paraspinous muscles to ligamentum
  • does NOT pass through supraspinous or intraspinous ligaments
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46
Q

contacting bone - troubleshooting

A

-withdraw needle and stylet to subQ fat, reposition the introducer and reinsert the needle

47
Q

needle touching the superior crest of spinous processes below the intererspace

A

redirect cephalad

48
Q

needle touching the inferior surface of spinous processes above the intererspace

A

redirect caudal

49
Q

repeatedly encounter bone

A

remove and reassess landmarks

50
Q

if patient experiences paresthesia during placement what do you do?

A
  • STOP
  • resolve ZINGER then proceed
  • if persistent - withdraw and reposition (bc prob hit nerve root yikes)
51
Q

what do you do if you get blood in your catheter

A

withdraw and replace!!!

52
Q

caudal anesthesia

A

distal approach to the epidural space through the sacral hiatus

53
Q

indications for caudal anesthesia

A
  • hemorrhoidectomy
  • chronic pain patients
  • peds analgesia -inguinal herniorrhaphy, circumcision, perineal procedures
54
Q

anatomy for caudal anesthesia

A
  • technically difficult approach especially in adults, overall failure rate is about 5%
  • sacral anatomy adults = variation in size, shape and orientation of hiatus
  • sacral anatomy peds = more reliable
55
Q

caudal anesthesia positioning

A
  • prone on flexed table or with pillow under the pelvis
  • legs spread and externally rotated
  • laterally positioned for peds
56
Q

caudal approach procedure

A
  • puncture sacral hiatus
  • adjust needle angle
  • advance 1-2 cm
57
Q

dosing for caudal

A
  • 0.5-1 mL/kg of body weight
  • varying LA concentrations
  • 2.5 mg/kg body weight
58
Q

caudal in adults

A
  • test dose
  • incremental injections following negative aspiration
  • sacral anesthesia 12-15 mL
  • lower extremity procedures 20-30 mL
59
Q

caudal complications

A
  • high failure rate (false passages like bone/subQ)
  • inadvertent IV injection or catheter placement
  • dural puncture
60
Q

combined spinal epidural (CSE)

A
  • initial subarachnoid injection followed by epidural catheter placement and subsequent administration of epidural medications
  • allows for rapid relief of pain or induction of regional anesthesia by the rapid onset of the spinal drugs and subsequent administration of medications for prolonged anesthesia
  • benefits of both spinal and epidural anesthesia
61
Q

CSE two level

A
  • spinal placed first

- epidural catheter placed 1-2 levels above

62
Q

CSE one-level

A
  • placement of epidural needle
  • spinal needle passes through
  • small intrathecal dose injected
  • epidural catheter placed
63
Q

CSE additional concerns

A
  • intrathecal opioid effects on fetus
  • inability to ambulate after receiving narcotics
  • maternal hypotension and itching
64
Q

CSE potential complications

A
  • failure to obtain intrathecal or epidural
  • catheter migration
  • increased spinal level
  • metallic particles
  • PDPH
  • neurologic injury
65
Q

Obese patient and epidural anesthesia

A
  • spinous processes more difficult to palpate, adipose tissue distorts landmarks
  • sitting position may provide more flexion
  • feet on stool or criss cross applesauce
  • assistant at bedside throughout procedure
  • consider ultrasound
66
Q

neuraxial imaging

A
  • US can identify epidural space more accurately than physical exam (71% vs 30%)
  • two scanning planes offer acoustic windows for the assessment of spinal anatomy
  • use low frequency curvalinear transducer
67
Q

ultrasound assisted

A
  • most common approach in adults
  • two scanning planes to determine level and midline
  • identify space, mark it, then stick it
68
Q

real time

A
  • feasible in peds population; caudal depth to space more shallow and angle flat
  • limited studies on adults
69
Q

what are the two scanning windows of neuraxial imaging

A
  • parasagittal

- axial

70
Q

parasagittal

A
  • paramedian, longitudinal view
  • off to sides and angle in toward midline
  • find level - start at sacrum, next see ligament (L5), notch level with marker
71
Q

axial

A
  • transverse, midline view
  • find spinous processes, know where to NOT go
  • spinous process = unicorn or traffic cone
  • space = bat sign
72
Q

metabolism of LA in CSF

A
  • little to none
  • absorbed into plasma and metabolized based on physiochemical properties
  • adding vasoconstrictors will slow absorption and prolong block
73
Q

esters

A
  • procaine
  • chloroprocaine
  • tetracaine
74
Q

amides

A
  • lidocaine
  • mepivacaine
  • ropivacaine
  • bupivacaine
75
Q

procaine

A
  • pKa - 8.9
  • % ionized - 97%
  • % protein bound - 6%
  • onset - slow
  • DOA - 60-90 min
76
Q

cholorprocaine

A
  • onset - fast

- DOA - 30-60 min

77
Q

tetracaine

A
  • pKa - 8.5
  • % ionized - 93%
  • % protein bound - 94%
  • onset - slow
  • DOA - 180-600 min
78
Q

lidocaine

A
  • pKa - 7.9
  • % ionized - 76%
  • % protein bound - 64%
  • onset - fast
  • DOA - 90-120
79
Q

mepivacaine

A
  • onset - fast

- DOA - 120-240 min

80
Q

ropivacaine

A
  • onset - slow

- DOA - 180-600 min

81
Q

bupivacaine

A
  • pKa - 8.1
  • % ionized - 83%
  • % protein bound - 95%
  • onset - slow
  • DOA - 180-600 min
82
Q

density of block

A

has to do with the concentration of the LA

83
Q

spread of block

A

has to do with the volume
cephalad to caudal spread
positioning
elderly, preggo

84
Q

how much LA do you inject into epidural space at a time

A

no more than 3-5 mL and ONLY after negative aspiration

85
Q

caudal dosing

A

2 mL/segment

86
Q

lumbar dosing

A

1 mL/segment

87
Q

thoracic dosing

A

0.7 mL/segment

88
Q

epinephrine additive

A
  • alpha 1 agonist
  • concentration added 1:200,000 or 5 mcg/mL
  • will prolong the effect of short-acting LAs by keeping it in the space
89
Q

clonidine additive

A
  • not a vasoconstrictor
  • selective alpha2 agonist
  • when mixed with lido or bupivacaine has synergistic effects for labor analgesia
  • potentially some direct action on the nerves
90
Q

epidural opioid additive

A

combination of preservative free opioids and LAs provides better analgesia then if either drug is used alone
-most commonly used = fentanyl and morphine (ITCHY)

91
Q

fentanyl additive

A
  • HIGH lipid solubility
  • PK and PD similar to systemic admin
  • provides profound analgesia
  • dose = 50-100 mcg
  • onset = 3-5 min
  • DOA = 1-2 hours
92
Q

morphine additive

A
  • HIGHLY polarized, not very lipid soluble
  • PK/PD similar to systemic admin
  • provides profound analgesia
  • dose 2-4 mg
  • onset 10-15 min
  • DOA 8-10 hrs
  • AEs = itching and urinary retention
93
Q

patient controlled epidural

A
  • low concentration of infusion with additive
  • augment effect of LA
  • patient has ability to inject additional LA if needed
94
Q

GOAL

A

block A delta and C fibers

drug concentration typically exceeds requirement for all nerve types

95
Q

a alpha

A

proprioception, motor

last block onset

96
Q

a beta

A

touch, pressure

intermediate block onset

97
Q

a gamma

A

muscle tone

intermediate block onset

98
Q

a delta

A

pain, cold temperature touch

  • 1-5 micrometers in diameter
  • heavy myelination
  • intermediate block onset
99
Q

b fibers

A

preganglionic autonomic vasomotor

  • <3 micrometers in diameter
  • light myelination
  • early block onset
100
Q

C sympathetic fibers

A

postganglionic vasomotor

early block onset

101
Q

C dorsal root fibers

A
  • pain, warm and cold temperature, touch
  • 0.4-1.2 micrometers in diameter
  • no myelination
  • early block onset
102
Q

B fiber block

A
  • rapid
  • hypotension r/t level
  • T 4 = cardiac accelerator fibers
  • drop in BP first sign
  • N/V may follow
103
Q

A delta and C pain fibers

A
  • these fibers along with temperature follow b fibers
  • unable to discriminate light touch or temperature
  • temperature discrimination mirrors sensory loss
104
Q

a alpha, a beta, a gamma

A

LAST

  • touch a proprioception
  • surgical muscle relaxation
  • may feel pressure
105
Q

nerve block onset fibers from earliest to last

A
  • B
  • C and A delta
  • A gamma
  • A beta
  • A alpha
106
Q

evaluation of onset

A
  • asses every 2-3 min
  • frequent assessments - BP/VS
  • physiologic changes closely resemble block level
  • level determined easiest by assessing sensory changes
  • distribution of spread can be manipulated by adjusting level of OR table
107
Q

autonomic blockade

A

usually 2 levels higher than level of sensory block

108
Q

motor block

A

upper limit generally two levels below sensory block

109
Q

complications of epidural anesthesia

A
  • hypotension
  • intercostal muscle paralysis
  • apnea/phrenic nerve paralysis
  • paresthesias
  • subarachnoid or epidural hematoma
  • meningitis/epidural abscess
  • chemical meningitis
  • cauda equina syndrome
  • transient neurologic symptoms
  • new nervous system lesion
  • exacerbation of preexisting neurologic disease
  • N/V
  • urinary retention
  • PDPH
110
Q

Post dural puncture headache (PDPH)

A
  • results from compromise in dura

- risk factors include - needle size and type, patient population (young, female, preggo)

111
Q

S/S PDPH

A
  • bilateral frontal or retroorbital or occipital
  • extends into neck
  • photophobia
  • nausea
  • positional
112
Q

PDPH treatment

A
  • conservative for first 12-24 hours (recumbent position, analgesics, fluids, caffeine, stool softeners and soft diet)
  • epidural blood patch
  • if that doesn’t work consider other sources
113
Q

epidural blood patch

A
  • injecting 15-20 mL of autologous blood
  • below initial puncture site (1-2 levels)
  • 90% will respond to initial therapy