EPIDEMIOLOGY Flashcards
study of distribution and determinants of diseases;
BACKBONE OF DISEASE PREVENTION
Epidemiology
components of epidemiology
Population
Distribution
Factors (Risk and Protective)
Father of Modern Epidemiology
John Snow
Role of Environment on health and disease
Hippocrates
First to employ quantitative methods in describing populatio
John Graunt
Cholera
John Snow
Vaccine for smallpox
Edward Jenner
Association between smoking and lung cancer
Doll and Peto
Epidemiologic concept of disease; >1 factor to cause disease
Mulitiple Causation
Components of Epidemiologic Triangle
Host
environment
Agent
epidemiologic concept stating that the effectsnever depend on a single isolated cause but rather each link is the result of a complex genealogy of antecedents
Web of causation
Environment is the fulcrum and either agent or host factors tip the balance to cause disease
Lever or Balance
The wheel
Man is at the center with its genetic makeup
surrounded by biological, social and environmental factors
invasion and multiplication of microorganisms that are not normally present within the body
infection
presence of FOREIGN MATERIAL that adulterates or renders a material impure
Contaminantion
Development ON the body of a pathogenic agent
infestation
Transmission of infection by direct contact, droplet spread or contaminated fomites
Contagion
Types of epidemiological approaches
Descriptive - determinants and distribution of disease
Analytical - tests hypothesis
Interventional/Experimetal- new clinical trials
Evaluational - measures effectivenesss of different health services and programs
Types of epidemiologic studies
OBSERVATIONAL
- Descriptive
- Analytic
EXPERIMENTAL
- RCT
- Field Trial
- Community Trial
Both descriptive and analytical study
Cross sectional study
type of study - describes distribution of cases by the variables of person, place and time to study and explain acute outbreaks of diseases; follow trends of diseases
GENERATE HYPOTHESIS
Descriptive Study
Concerned with determining causes of disease occurence
TESTS HYPOTHESIS
Analytical
increase in the number of cases more or less regularly every around 5 years due to accumulation of susceptible births
CYCLIC INTRINSIC VARIABILITY
fluctuation of disease occurence during a year reflecting climactic changes
seasonal variation