Epidemiology Flashcards
Study of disease, injury and death
Epidemiology
According to CDC, it is the study
(scientific, systematic, and data-driven) of
the distribution and determinants of
health-related states and events (not
just disease) in specified populations
(neighborhood, school, city, state, country, global)
According to WHO, it is the study of
the distribution and determinants of
health-related states or events
(including disease), and the application
of this study to the control of diseases
and other health problems
Epidemiology
Refers to descriptive epidemiology
When (time), Where (place), Who
(person)
Distribution
incidence, prevalence
and mortality rates
Frequency
- time, place, person
Pattern
Refers to analytic epidemiology
Causes, risk factors, modes of
transmission (why and how)
Causes - agents
Risk factors - exposure to sources
Examples: smoking, obesity, high blood
pressure, diabetes, infections, genetics
Determinants
Veni, vidi, vici
(I came, I saw, I conquer)
Theory of four body humors produced
within the body
Earth - blood and brain
Air - phlegm and lungs
Fire - black bile and spleen
Water - yellow bile and gallbladder
Hippocrates (460 BCE - 370 BCE)
Seeds of disease
Girolamo Fracastoro (Circa 1476 - 1553)
Disease as an external thing called an
ens which could attack any organ of the
body
Paracelsus and JB van Helmont
First to demonstrate microorganisms
Antoni van Leeuwenhoek (1632 - 1723)
Germ Theory, germ cause disease
Developed vaccine against anthrax and
biological treatment for rabies
Louis Pasteur (1822 - 1895)
one germ can cause
one disease
Biological specificity
Perfected methods for growing pure
colonies of bacteria
Developed autoclaves for sterilizing
equipment
Introduced photography to demonstrate
what he had seen through his microscope
Identified some of the key disease-
Robert Koch (1843 - 1910)
Antiseptic surgery which developed into
aseptic surgery
Joseph Lister (1827 - 1912)
Named the disease syphilis in a poem
Notion of seeds of disease
Girolamo Fracastoro (1476
His study on cholera reinforced his notion
that it was not transmitted by miasma
but through contaminated water
John Snow (1813 - 1858)
First thorough notion of a germ theory
of disease
Studied yeast, bacteria, and viruses
Louis Pasteur (1882
Use of carbolic acid dressings to
disinfect surgical wounds
Introduced aseptic technique
Joseph Lister (1827
Discovered causative organisms of
tuberculosis and cholera
Robert Koch
Study led to a better understanding of the
nature of viruses and their relationship
to the cells of the organism they
invade
Martinus Beijerinck
Influenced microscopy, tissue staining, embryology, chemotheraphy and
immunology
Theory of the chemical nature of
antigens and antibodies (lock and key)
Paul Ehrlich (1854 - 1915)
Developed a polio vaccine that used an
attenuated strain of the virus
Albert Sabin (1906
Coined the term prion and came up with
the theory behind how these misfolded
proteins cause grave disease
Stanley Prusiner (1942)
Worked on the retroviruses, of which
HIV is the most significant
Francoise Barre-Sinoussi (1947)
–
includes the study of the frequency, patterns, and causes of health-related
states or events in populations, and the
application of that study to address public
health issues
Basic science of public health, epidemiology
Microbes: bacteria, virus, fungi, protozoa
Agent
The human capable of developing the
disease: genetics, ethnicity, socioeconomic status, sex, and
gender
Host
- Lead and heavy metals
- Air pollutants and other
asthma triggers
Environmental exposures