Eosinophilia Differential Flashcards
1
Q
What is eosinophilia defined as?
A
greater than 1.5 x10^9/L
2
Q
What should you do next?
A
Is there a secondary cause requiring specific treatment nor directed at eosinophilia?
3
Q
If yes, then what?
A
treat as appropriate. If it resolves, stop.
4
Q
What if it doesn’t resolve?
A
continue evaluation for presumed hypereosinophilia syndrome (HES0
5
Q
What is there isn’t a secondary cause requiring specific treatment nor directed at eosinophilia?
A
continue evaluaiton for presumed HES to include:
- routine blood studies
- serum troponin
- serum tryptase and B12 levels
- FIP1L1/PDGRFa analsyis
6
Q
What if the FIP1L1/PDGRFa comes back positive?
A
try treating with Imatinib
