Enzymes of Cholesterol Synthesis Flashcards
Desmolase: Substrate/Product + Alter name + Location
Substrate: Chlesterol
Product: Pregnenolone
Alter: CYP11A1
Location: Mitochondrai
3B: Substrate/Product + Location
Substrate: Pregnolone
Product: Progesterone
Location: ER
17a: Substrate/Product + Alter name + Location
Substrate: Pregnenolone or Progesterone
Product: 17-hydroxypregnenolone or 17-hydroxyprogesterone
Alter: CYP17A1
Location: ER
21: Substrate/Product + Alter name + Location
Substrate: Progesterone or 17-hydroxyprogesterone
Products: Deoxycorticosterone or 11-deoxycortisil
Alter: CYP21A2
Location: ER
11: Substrate/Product + Alter name + Location
Substrate: Deoxycorticosterone or 11-deoxycortisol
Products: COrticosterone or Cortisol
Alter: CYP11B
Location: Mitochondria
18: Substrate/Product + Alter name + Location
Substrate: Corticosterone
Products: Aldosterone
Alter: CYPB2
Location Mitochondria
Aromatase:Substrate/Product + Alter name + Location
Substate: Androstenedione or Testosterone
Product: Estradiol
Alter: CYP19
Location ER