Drugs Post-Midterm Flashcards

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0
Q

Inhibitors Cox-1 & Cox-2

A

Aspirin(irreversible)
Indomethacin
Phenylbutazone(reversible)

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1
Q

Inhibitor Phospholipase A2

A

Corticosteroids (cortisol)

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2
Q

Activators COX-2

A

Cytokines, Endotoxin, GF, Tumor promoters

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3
Q

Selective inhibitors COX-2

A

Celecoxib, Coticosteroids

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4
Q

Inhibitors Thromboxane synthase

A

Dazoxiben, Dipyridamole

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5
Q

Inhibitors 5-Lipoxygenase

A

Benoxaprofen

Zileuton

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6
Q

Drugs that treat Asthma inhibit what?

A

1) Release of Arachidonic acid
2) Inhibit 5-Lipoxygenase
3) Inhibit cysteinyl-leukotreine receptor

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7
Q

Niacin

A

reduces LDL-cholesterol and TAGs, and raises HDL

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8
Q

Isoniazid

A

Inhibits PLP (coenzyme for ALAS)

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9
Q

Phenobarbital

A

Barbiturates should not be administered to patients suffering from AIP

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