Enzymes and Digestion Flashcards

1
Q

What is metabolism

A

the sum of all the chemical reactions that occur in a cell

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2
Q

Anabolic Reactions

A
  • building up molecules
  • requires input of energy
  • endergonic reaction
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3
Q

Catabolic Reactions

A
  • breaking down molecules
  • release energy
  • spontaneous reaction
  • exergonic reaction
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4
Q

Metabolic Pathways

A

cellular reactions are that are apart of of linked reactions

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5
Q

enzymes

A

protein molecule that acts as organic catalyst to speed up chemical reactions without being consumed

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6
Q

Substrate

A

reactants in enzymatic reaction, A is substrate for E1, B is the products

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7
Q

peptide Hormones used to control metabolism

A

Thyroxin (T4) and triiodothyronine (T3)

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8
Q

Uses of T3 and T4

A

targets all body cells
increases metabolic rate
regulates growth and development

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9
Q

coenzymes

A

non-protein cofactors used to activate enzyme

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10
Q

example of coenzyme

A

vitamins and minerals

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11
Q

apoenzyme

A

protein cofactors used to activate enzyme

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12
Q

example of apoenzyme

A

hemoglobin

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13
Q

6 factors affecting enzymatic speed

A

substrate concentration
enzyme concentration
temperature
pH
enzyme inhibition
enzyme-substrate complex

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14
Q

What is the effect of substrate and enzyme concentration

A
  • enzyme activity increases because there are more collisions between substrate molecules and enzymes
  • more active enzyme sites = increase in activity for substrate binding
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15
Q

What is the effect of temperature on enzymatic speed?

A
  • slight increase temperature = increase enzyme activity ( more collisions between enzyme and substrates increases energy + movement)
  • slightly lowered temp = decreased enzyme activity
  • is temp too high/low, enzyme denatures
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16
Q

what is the effect of pH on enzymatic speed?

A
  • each enzyme has optimal pH where the reaction rate is highest
  • if pH is too high/low enzyme is denatured
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17
Q

What id enzyme inhibition?

A

when an active enzyme is blocked from combining with its substrate

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18
Q

What are the names of the inhibitors?

A

Competitive and non-competitive inhibitors

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19
Q

What is competitive inhibition

A

Competitive inhibition interferes with active site of the enzyme so substrate cant bind

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20
Q

what is non-competitive inhibitors

A

changes the shape of enzyme so it can’t bind to substrate

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21
Q

What is feedback inhibition

A

When the reaction product interferes with the enzyme that helped build it. binds to another active site that’s different from the one attached to original reactant

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22
Q

What is energy of activation

A

when molecules react with one another, energy is required. this is activation energy

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23
Q

What is enzyme-substrate complex

A

enzyme active site goes under a change in shape to accommodate substrate. AKA induced fit model

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24
Q

What is homeostasis

A

maintenance of constant internal balance

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25
Q

What does a homeostatic mechanism in the body contain

A

sensor, regulatory center, and effector

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26
Q

What is negative feedback

A

the primary homeostatic mechanism that keeps variables close to its set point. The response reverses the change in controlled conditions.

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27
Q

What is positive feedback?

A

homeostasis mechanism that brings a great change in the same direction and intensifies over time. The response strengthens change in controlled conditions.

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28
Q

What does the endocrine system consist of

A

glands, tissues that secrete hormones

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29
Q

What is a stimulus

A

a change detected that triggers negative feedback response

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30
Q

what is an antagonistic hormone?

A

the hormone that has opposite effects to a stimulus and is used to maintain homeostasis. Example is insulin and glucagon

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31
Q

what is the digestive tract?

A

the digestive tract is a tube with special regions and organs between mouth and anus

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32
Q

what is the function of the digestive system

A

to ingest food, digest nutrients and eliminste indigestable reminas

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33
Q

what are the stages of the digestive system

A

digestion, absorption, and elimination

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34
Q

Describe the breakdown of biological molecule protein

A

protein to peptide to amino acid

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35
Q

Describe the breakdown of biological molecule carbs

A

carbs to maltose to glucose

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36
Q

Describe the breakdown of biological molecule fats and lipids

A

fats and lipids to glucose and fatty acids

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37
Q

Describe the breakdown of biological molecule nucleic acid

A

the nucleic acid to nucleotides to S,P,B

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38
Q

How is the roof of the mouth formed

A

formed by soft and hard palates that separate it from the nasal cavities

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39
Q

What is the role of mechanical digestion

A

the teeth being mechanical digestion with help from the tongue and start digestion

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40
Q

What are the three pairs of salivary glands

A

parotid, submandibular, sublingual

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41
Q

What is the enzyme found in the mouth

A

salivary amylase

42
Q

what does amylase break down

A

starch and maltose

43
Q

describe chemical digestion

A

the three salivary glands send saliva amylase for digestion in the mouth. The tongue mixes chewed food with saliva to form a mass called a bolus.

44
Q

What happens inside the pharynx?

A

air passage and food passage meet at pharynx

45
Q

Give an example of involuntary reflex action.

A

Swallowing food in the pharynx

46
Q

What is the esophagus

A

muscular tube that moves food into the stomach

47
Q

What is peristalsis and explain how it works

A

begins in the esophagus and moves food through the digestive system

48
Q

What is the function of the cardiac valve

A

prevents food from backing up into the esophagus

49
Q

What is the pH in the stomach

A

2

50
Q

what are the folds in the stomach called

A

rugae. they help stomach expand so it can hold 2L

51
Q

where is alcohol absorbed

A

in the stomach

52
Q

Explain the process happening in the stomach

A

food is churned in the stomach for 2-3 hours while being mixed with gastric juices for digestion of proteins to peptides and water and mucus

53
Q

What do gastric juices contain

A

water, HCL, and pepsinogen

54
Q

What does pepsinogen become

A

pepsinogen becomes pepsin in HCL

55
Q

what are ulcers caused by

A

stress and bacterial infections

56
Q

what is the pH in the small intestine

A

8

57
Q

what is the length of the small intestine

A

7 meters

58
Q

what is the duodenum

A

the first 25cm of the small intestine that receives bile and pancreatic juice

59
Q

What is bile

A

emulsifier of lipids, not an enzyme. also is mechanical digestion

60
Q

Were is bile produced

A

produced in liver and stored in gall bladder

61
Q

What does pancreatic juice contain

A

contains sodium bicarbonate that neutralizes acid.

62
Q

Pancreatic amylase

A

for digestion of starch to maltose

63
Q

trypsin

A

protein to peptides

64
Q

lipase

A

lipids to glycerol and fatty acids

65
Q

nuclease

A

nucleic acids to nucleotides

66
Q

what’s produced in intestinal wall of duodenum

A

enzymes of small intestines

67
Q

peptidase

A

breaks down peptides to amino acids

68
Q

maltase

A

breaks down maltose to glucose

69
Q

nucleosidase

A

breaks down nucleotides to sugar, phosphate, and base

70
Q

what are the walls of small intestine called

A

jejunum, ilium

71
Q

what are villi

A

finger-like projections where nutrients are absorbed

72
Q

what do villi have

A

microvilli that increase surface area

73
Q

jejunum and ilium…

A

are convoluted have have villi where nutrients are absorbed into the cardiovascular and lymphatic systems

74
Q

what deos each villus have

A

it’s own capillary network

75
Q

lacteal

A

small lymphatic capillary in a villus

76
Q

what does large intestine consist of

A

rectum, anus, and colon

77
Q

purpose of large intestine

A

absorb water, sals, vitamins and nutrients

78
Q

what is stored in the rectum?

A

indigestible material

79
Q

explain process of anus and rectum

A

indigestible material is saved in the rectum until the anus allows defecation.

80
Q

How do you release defecation

A

stretch receptors in rectum send signals to spinal cord and brain to tell your body to release

81
Q

What are the bacteria in your feces

A

obligate anaerobes and facultative anaerobes

82
Q

what is the function of obligate anaerobes and facultative anaerobes

A

to break down indigestible material and produce vitamins

83
Q

what are the three accessory organs

A

pancreas liver and gallbladder

84
Q

why are they called accessory organs

A

accessory organs of digestion because their secretions assist digestion

85
Q

how do accessory organs work

A

send secretions to the duodenum

86
Q

functions of pancreas

A
  • produce insulin- when sugar is high
  • secrete glucagon where sugar is low
87
Q

what does insulin act on

A

liver, muscle, adipose

88
Q

what does glucagon act on

A

liver and adipose tissue

88
Q

what does glucagon act on

A

liver and adipose tissue

89
Q

what does the liver store glucose as

A

glycagon

90
Q

what are 6 functions of liver

A

store iron and vitamins
make plasma proteins
produce urea from amino acids
detoxify blood
regulate cholesterol levels while producing bile salts
remove bilirubin from blood cells with bile

91
Q

what regulates digestive juice

A

nervous system and hormones

92
Q

gastrin

A

triggered by protein, produced in the lower stomach and travels through stomach to produce digestive juice

93
Q

secretin

A

produced by the duodenum wall and simulated by acid travels to the pancreas and gall bladder where it releases bile and pancreatic juice

94
Q

Cholecystokinin (cck)

A

produced by the duodenum wall and simulated by fat and proteins travels to the pancreas and gall bladder where releases bile and pancreatic juice

95
Q

Calcitonin

A

produced by the thyroid gland and simulated by high calcium levels. Travels through blood stream and deposits extra calcium in to the bones

96
Q

Parathyroid Hormone (PTH)

A

produced by parathyroid glands and simulated by insufficient calcium levels. travels to the bones and releases calcium from bone to get kidneys and intestines to absorb calcium.

97
Q

Calcitriol

A

produced by kidneys and simulated by low calcium levels. Travels to the intestine and promotes the absorption of calcium in the intestines. Active form of vitamin D

98
Q

leptin

A

produced in adipose tissues and simulated by the fat increase in the body. Travels to the hypothalamus and lowers your apetite.

99
Q

Enzymes found in pancrease

A

pancreatic amylase
trypsin
lipase
nucleolus

100
Q

enzymes found in duodenum

A

maltase
peptidase
nucleosidase