Enzymes Flashcards

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1
Q

Enzymes

A

They are proteins that speed up chemical reactions. Without enzymes, reactions can still occur but they would be too slow to support life. It is a catalyst.

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2
Q

Globular Proteins

A
They form amino acids that have metabolic functions. They form enzymes.
They can help with: 
- Cell movement
- Transport
- Storage
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3
Q

Catalyst

A
  • They increase the rate of the reactions in the body.

- Without enzymes, metabolism would be too slow to sustain life.

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4
Q

Substrate

A

A substance is acted upon by an enzyme. It is what binds to an enzyme which gives out a product.

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5
Q

Active site

A

only specific molecules can fit into it, so enzymes are highly specific in their action.

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6
Q

Lock and Key

A

the action of the enzyme and the substrate can be likened to a lock and key.

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7
Q

Induced-fit

A

the substrates change the shape of the enzyme – they make the enzyme fit the substrates.

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8
Q

Denaturing

A
  • This means some of the bonds within it are destroyed and the whole enzyme molecule changes shape, as a result the active site will also change shape. So the enzyme is less effective, possibly even useless.
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9
Q

Optimum temperature

A
  • Enzymes are highly sensitive to temperature and pH levels (acidity or alkalinity).
  • This means they can only act within a certain range of pH and temperature values.
  • For example, in human cells enzymes work best between 35°C and 40°C.
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10
Q

Metabolic poisons

A

• The reason is that such substances may block entry to or occupy active sites temporarily if they have the right shape

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11
Q

Optimum concentration

A

• When all enzymes have a substrate molecule to work on or when all substrates have an enzyme to bind to, we call that the point of OPTIMUM CONCENTRATION.

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12
Q

Activation energy

A

• Like all catalysts, enzymes work by lowering the ACTIVATION ENERGY for a reaction, thus dramatically increasing the rate of the reaction.

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13
Q

Intracellular

A

(inside the cell) enzymes – where they speed up and control metabolic reactions

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14
Q

Extracelluar

A

produced and secreted by the cells and act outside the cell. They include digestive enzymes, which breakdown food in the gut.

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15
Q

Coenzymes

A
  • are small organic molecules that TRANSPORT chemical groups from one enzyme to another.
  • Some of these chemicals such as riboflavin, thiamine and folic acid are VITAMINS
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16
Q

Product

A

A product is something “manufactured” by an enzyme from its substrate.

17
Q

Enzyme characteristics

A
  1. All enzymes have an active site
  2. They are very specific
  3. They are recycled
18
Q

Enzyme action

A
  1. The enzyme binds to the substrate
  2. The enzyme catalyzes the substrate into a product
  3. The enzyme releases the product
19
Q

What happens after the enzyme has completed the reaction?

A

It goes back to normal and produces more products

20
Q

Has the enzyme chemically changed after a reaction?

A

No

21
Q

How does an enzyme work?

A

It lowers the activation energy for a reaction. Therefore, the rate of the reaction is faster

22
Q

What are the two main factors that influence an enzymes effectiveness?

A
  • Temperature

- pH

23
Q

What is the optimum environment for most enzymes?

A

Temperature: 37 degrees
pH: 7 (neutral)

24
Q

What happens to an enzyme outside its optimum environment?

A

It will denature.

25
Q

Reaction formula

A

Substrate –> product

26
Q

What is the rate of a chemical reaction?

A

1000 times a second

27
Q

Naming Enzymes

A

Most enzymes end in ‘ase” however pepsin, trypsin, rennin and ptyalin do not

28
Q

Where are enzymes made?

A
  • They are made in the cytoplasm