Enzymes Flashcards

Created using notes from Week 9 of class.

1
Q

Enzymes are classified as which type of polymer?

A

Proteins.

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2
Q

Enzymes are formed from chains of this monomer:

A

Amino acids.

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3
Q

The general function of enzymes are to serve as:

A

Biological catalysts.

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4
Q

What does it mean when something is an organic catalyst?

A

It speeds up the rate of a reaction by lowering the activation energy.

The activation energy is the energy needed for reactants to chemically react.

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5
Q

Enzymes may work on ________ reaction at a time, but may be used ________ times.

A

Enzymes may work on one reaction at a time, but may be used many times.

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6
Q

The lock and key aspect of enzymes means:

A

Enzymes are specific and will only work with particular substrates.

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7
Q

Where does the substrate bind with the enzyme?

A

The activation site.

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8
Q

An enzyme-catalyzed reaction saves ________ and __________.

A

An enzyme-catalyzed reaction saves time and energy.

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9
Q

What does it mean for enzymes to have an induced fit model?

A

It means that the active site changes in shape slightly to best fit the substrate.

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10
Q

True or False: Once the enzyme has changed shape slightly due to the induced fit model, it cannot return to its original state.

A

False.

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11
Q

Metabolism is. . .

A

. . . the sum of all reactions that occur in a cell.

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12
Q

A reaction during which we start out with a polymer and the products are monomers is:

A

A degradative reaction (hydrolysis).

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13
Q

A reaction during which we start out with monomers and the product is a polymer is:

A

A synthetic reaction (dehydration synthesis).

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14
Q

List the four factors that affect the rate of enzyme activity:

A

Substrate concentration, pH, temperature and enzyme concentration.

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15
Q

Enzyme activity ________ as substrate concentration increases, until all active sites are filled and enzyme activity will _____________.

A

Enzyme activity increases as substrate concentration increases, until all active sites are filled and enzyme activity will level off.

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16
Q

Enzyme activity ________ as temperature increases, until the temperature becomes high enough that enzyme activity will ________ because ___________.

A

Enzyme activity increases as temperature increases, until the temperature becomes high enough that enzyme activity will cease because the enzymes have denatured.

17
Q

Why do higher temperatures increase enzyme activity?

A

Because the substrates and enzymes move faster, will collide and lead to faster reactions.

18
Q

Optimal pH for an enzyme is:

A

The pH at which the rate of reaction is highest.

19
Q

Change in pH may affect an enzyme’s. . .

A

. . . ability to bond by denaturing the enzyme.

20
Q

True or false: Once an enzyme is denatured by a change in pH, it cannot return to its original form.

A

False.

If the enzyme is returned to its optimal pH, it will return to its native form.

21
Q

True or false: Once an enzyme has been denatured by exposure to extreme heat, it cannot return to its original state.

A

True.

22
Q

These molecules sit in the active site to aid in the bonding of an enzyme and a substate.

A

Cofactors and coenzymes.

23
Q

Cofactors are:

A

Ions.

24
Q

Coenzymes are:

A

Organic.

25
Q

This molecule sits in the active site and blocks the substrate from bonding with the enzyme.

A

A competitive inhibitor.

26
Q

This molecule sits on the allosteric site and causes the enzyme to change shape slightly.

A

A non-competitive inhibitor.

27
Q

The role of an inhibitor is to:

A

Restrict enzyme activity, which may limit the amount of a particular substrate’s production.

28
Q

Enzyme concentration is controlled by:

A

Genetic activation.

29
Q

An enzyme pathway is:

A

Like an assembly line, where the product of one enzyme becomes the substrate of the next.

30
Q

Feedback inhibition is:

A

Wherein the product of an enzymatic pathway suppresses the activity of those enzymes involved in the product’s creation.