Enzymes Flashcards
Enzymes may recognize and catalyze:
⊚ A single substrate
⊚ A group of similar substrates
⊚ A particular type of bond
Acted upon by the enzyme and specific
Substrate
Acted upon by the enzyme and specific but different form with the same action
Isoenzyme
Non-protein molecule of a conjugated enzyme
Cofactor
Activator/Metal ions
Inorganic cofactor
Organic cofactor
Coenzyme
Polypeptide portion of a conjugated enzyme and inactive enzyme
Apoenzyme
Apoenzyme + Cofactor
Holoenzyme
⊚ Also known as zymogen
⊚ Inactive form or precursor of enzyme
⊚ It is then converted, usually by proteolysis,
to the active form when it has reached the site of its activity
Proenyzme
Enzyme Commission Nomenclature (E.C.)
⊚ 1st digit – class
⊚ 2nd digit – subclass
⊚ 3rd and 4th digit – serial number
Oxidation and reduction
Oxidoreductases
Transfer of functional groups other than
hydrogen from one substrate to another
Transferases
transfer of amino group
Transaminases
transfer of phosphate group from
ATP to ADP + phosphorylated product
Kinases
• is an enzyme that catalyzes a hydrolysis
reaction in which the addition of a water molecule to a bond causes the bond to break
• Central to the process of digestion
Hydrolases