Enzyme Terminology & Rate-Limiting Steps

Question 1

What is the term for an eyzme that:

catalyzes a transfer of a phosphate group from high-energy molecule (ATP) to a substrate

Answer 1

kinase

Question 2

What is the term for an eyzme that:

adds inorganic phosphate onto substance without using ATP

Answer 2

phosphorylase

Question 3

What is the term for an eyzme that:

removes phosphate group from substrate

Answer 3

phosphatase

Question 4

What is the term for an eyzme that:

catalyzes oxidation-reduction reactions

Answer 4

dehydrogenase

Question 5

What is the term for an eyzme that:

adds hydroxyl group onto substrate

Answer 5

hydroxylase

Question 6

What is the term for an eyzme that:

transfers CO₂ groups with the help of biotin

Answer 6

carboxylase

Question 7

What is the term for an eyzme that:

relocates a functional group within a molecule

Answer 7

mutase

Question 8

What is the term for an eyzme that:

joins two molecules together using a source of energy

Answer 8

synthase / synthetase

Question 9

What is the rate-limiting enzyme of glycolysis?

Answer 9

PFK-1

Question 10

What is the rate-limiting enzyme of gluconeogenesis?

Answer 10

Fructose-1,6,-bisphosphatase 1

Question 11

What is the rate-limiting enzyme of TCA cycle?

Answer 11

Isocitrate dehydrogenase

Question 12

What is the rate-limiting enzyme of glycogenesis?

Answer 12

glycogen synthase

Question 13

What is the rate-limiting enzyme of glycogenolysis?

Answer 13

glycogen phosphorylase

Question 14

What is the rate-limiting enzyme of HMP shunt?

Answer 14

glucose-6-phosphate dehydrogenase (G6PD)

Question 15

What is the rate-limiting enzyme of de novo pyrimidine synthesis?

Answer 15

carbamoyl phosphate synthetase II

Question 16

What is the rate-limiting enzyme of de novo purine synthesis?

Answer 16

glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase

Question 17

What is the rate-limiting enzyme of urea cycle?

Answer 17

carbamoyl phosphate synthetase I

Question 18

What is the rate-limiting enzyme of fatty acid synthesis?

Answer 18

acetyl-CoA carboxylase

Question 19

What is the rate-limiting enzyme of fatty acid oxidation?

Answer 19

carnitine acyltransferase I

Question 20

What is the rate-limiting enzyme of ketogenesis?

Answer 20

HMG-CoA synthase

Question 21

What is the rate-limiting enzyme of cholesterol synthesis?

Answer 21

HMG-CoA reductase