Enzyme Terminology & Rate-Limiting Steps Flashcards
What is the term for an eyzme that:
catalyzes a transfer of a phosphate group from high-energy molecule (ATP) to a substrate
kinase
What is the term for an eyzme that:
adds inorganic phosphate onto substance without using ATP
phosphorylase
What is the term for an eyzme that:
removes phosphate group from substrate
phosphatase
What is the term for an eyzme that:
catalyzes oxidation-reduction reactions
dehydrogenase
What is the term for an eyzme that:
adds hydroxyl group onto substrate
hydroxylase
What is the term for an eyzme that:
transfers CO2 groups with the help of biotin
carboxylase
What is the term for an eyzme that:
relocates a functional group within a molecule
mutase
What is the term for an eyzme that:
joins two molecules together using a source of energy
synthase / synthetase
What is the rate-limiting enzyme of glycolysis?
PFK-1
What is the rate-limiting enzyme of gluconeogenesis?
Fructose-1,6,-bisphosphatase 1
What is the rate-limiting enzyme of TCA cycle?
Isocitrate dehydrogenase
What is the rate-limiting enzyme of glycogenesis?
glycogen synthase
What is the rate-limiting enzyme of glycogenolysis?
glycogen phosphorylase
What is the rate-limiting enzyme of HMP shunt?
glucose-6-phosphate dehydrogenase (G6PD)
What is the rate-limiting enzyme of de novo pyrimidine synthesis?
carbamoyl phosphate synthetase II
What is the rate-limiting enzyme of de novo purine synthesis?
glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase
What is the rate-limiting enzyme of urea cycle?
carbamoyl phosphate synthetase I
What is the rate-limiting enzyme of fatty acid synthesis?
acetyl-CoA carboxylase
What is the rate-limiting enzyme of fatty acid oxidation?
carnitine acyltransferase I
What is the rate-limiting enzyme of ketogenesis?
HMG-CoA synthase
What is the rate-limiting enzyme of cholesterol synthesis?
HMG-CoA reductase
