environmental health and tox Flashcards
An Animal Feeding Operation by definition means you need to bring feed onto premises to feed animals for minimum of ___ days per year.
45 days
Toxic principle on Tall Fescue and clinical signs in what species?
Ergovaline alkaloids cause dry gangrene of digits, abdominal fat necrosis, agalactia in late gestation in horses and cattle
Black walnut (Juglans nigra) causes ____ clinical sign in horses?
Laminitis
Hoary alyssum (bertoa incana) can cause ____ clinical signs in ____ species?
Laminitis and dependent edema in horses
Death Camas (Zygadenus spp) toxic principle and clinical signs?
Alkaloids zygacine causes vasodilation , hypotension, bradycardia, seizures, death
4 main cardiotoxic plants?
Taxus spp (yews) Digitalis (foxglove, oleander, lily of the valley, dogbane), Grayanotoxins (rhodadendrons, azaleas, heath), Trematone (Eupatorium/ White snake root)
Main toxic principle and clinical signs for milkweeds (Asclepias)?
Cardiac and GI signs; cardenolides (cardiac glycoside)
Main components of acid rain?
Sulfur dioxide and nitrogen oxides
What size particulate matter lodges in nose/pharynx? What size lodges in lower airways?
PM10- nose; PM 2.5- lungs
Main toxin in Taxus spp and main clinical signs?
Alkaloids Taxine A and B; Cardiac and GI; sudden death
Main toxin in Persea americana (Avocado) and clinical signs?
Unknown toxin; cardiac (Horses, birds), SQ tissues, and mastitis… skin and seeds most toxic
5 plants causing hemolytic anemia?
Allium spp, Acer rubrum (red maple), Brassica spp, Melilotus officinalis (yellow sweet clover), Pteridium aquilinum (Bracken fern) in cattle esp
5 Plants that cause cyanide poisoning?
Wild cherry, choke cherry, Sorghum spp (Johnson grass, sudan grass), Arrograss, Elderberry
What color is blood in cyanide poisoning?
Cherry red
Toxic principle in moulded sweet clover hay?
Dicourmarol (anticoagulant)
4 Plants that cause methemoglobinemia?
Amaranthus spp (Pigweed,), Lambs quarters, Kochia spp (burning bush, fireweed), Sorghum spp (johnsongrass, sudan grass)
6 Plants that cause liver toxicosis?
Senicio, crotalaria, Cocklebur, Gossypol, alsike clover, Sago palms
5 Algae or mycotoxins that cause liver toxicosis?
Aflatoxin, fumonisin, sporodesmin, blue-green algae, amanita mushrooms
Senecio spp toxic principle and clinical signs?
Pyrrolizidine alkaloids and liver toxicosis (Hepatic insufficiency, HE, death)
Cockleburr (Xanthium spp) toxic principle and clinical signs?
Carboxytractyloside and hepatotoxic primarily in swine
Key species of blue-green Algae?
Microcystis and Anabena
2 Plants associated with photosensitization (primary)?
Buckwheat (Fagopyrum spp), St John’s wort (Hypericum)
4 Plants associated with nephrotoxicity?
Quercus spp (oaks), Amaranthus spp (redroot pigweed- swine), Lillium and Hemerocallis (lilies- cats),
5 Oxalate-containing plants?
Sorrel, dock, Amaranthus (pigweed), Rhubarb, Chenpodium album (Lamb’s quarters, greasewood, burning bush),
5 Plants with CNS signs?
Astralagus/Oxytroppis spp (locoweed), Yellow star thistle, Russian knapweed, Aesculus spp (Ohio buckeye), Morning glory seeds
5 Plants causing paresis/paralysis?
Larkspur (delphinium spp), macadamia nuts, Karwinskia (Coyotillo), Lathyrus spp (Vetches), Sorghum spp (horses- ataxia, urine dribbling)
Toxic principle locoweed and clinical signs?
Inhibits alpha mannosidase. Horses- ataxia; cattle/sheep: abortions, skeletal malformations
“Chewing disease” is caused by what?
Chronic ingestion of yellowstar thistle.
1ppm= ___mg/L?
1mg/L
Season where blue-green algae can be issue in freshwater sources?
Late summer early fall
For recreational waters and beaches, water quality is based on what two indicators?
Enterococcus and E. coli
Cause of blue baby syndrome?
Elevated nitrates in drinking water, which is converted to nitrites in the body and decreases oxygen carrying capacity of hemoglobin
Main concern with phosphorus in surface water?
Increases growth of algae and aquatic plants which consume all the oxygen
Lupine toxic principle and clinical signs?
Lupinine (alkaloid); crooked calf dz (cattle), neuro signs (horses, cattle, sheep)
Poison hemlock clinical signs?
Rapid neuro signs, death; subclinical dose can cause arthrogryposis in cattle
4 plants that cause seizures?
Water hemlock, milkweed, fitweed, dutchman’s breeches
3 plants that cause CNS depression?
Eupatoruim spp (White snakeroot), Isocoma wrightii (rayless goldenrod), Stipa robusta (sleepy grass)
4 Cholinergic blocking plants?
Datura stramonium (Jimson weed), Solanum spp (nightshades), Atropa belladonna (belladonna) Cestrum diurnum (Night blooming jessamine)
Toxic principle nightshades and clinical signs?
Solanine causes cholinesterase and GI irritation; ataxia, depression, GI signs
Who regulates disinfectants and antiseptics?
Disinfectants= EPA (used on inanimate things) Antiseptics = FDA (used on living things)
OSHA is part of what federal department? What about NIOSH
OSHA = dept of labor (regulatory/enforecement); NIOSH = Health and human services as part of CDC (research, advisement)
Aflatoxins clinical signs
p450 inhibitors; liver toxicosis in many species
What species is especially sensitive to carcinogenic properties of aflatoxins?
Trout get hepatocellular carcinomas.
Melamine combines with ____ to cause acute renal failure in cats
Cyanuric acid
Definition toxicant vs toxin?
Toxicant: any agent capable of producing a deleterious effect on a biological system.
Toxin: Poison that originates from biological processes
Definition threshold dose (toxins)?
Highest dose in which toxic signs are not seen
1ppm = ___ g/ton
0.91g/ton
Which plant can cause cyclops in sheep?
veratrum spp
What are effects of ground level ozone
Respiratory irritant and toxin, photosynthesis inhibitor
What are four common air pollutants associated with CAFOs?
Ammonia, H2S, methane, particulate matter
1ppm = ___ g/ton
0.91g/ton
Which plant can cause cyclops in sheep?
veratrum spp
Carbamate and organophosphate mechanism of action and clinical signs
Ach inhibitor; see SLUD signs, seizures, death
The PETS Act ammended the ____ act to include household pet in evacuation plans
Stafford Act
What are the four possible characteristics of hazardous waste?
Ignitability (flammable), Toxicity (fatal/harmful) , corrosivity (pH), Reactivity (explosive)
Which metal as found in the milk of dairy cattle after feeding round bales used for target practice? a. Lead b. Silver c. Copper d. Arsenic e. mercury
A. Lead
Which metal causes bloody guts and is found in highest levels in the kidney? a. Lead b. Silver c. Copper d. Arsenic e. mercury
D. Arsenic
Which metal has highest levels in the brain an is an environmental concern? a. Lead b. Silver c. Copper d. Arsenic e. mercury
E. Mercury
Which metal has highest levels in the liver but causes gunmetal kidneys in sheep? a. Lead b. Silver c. Copper d. Arsenic e. mercury
C. Copper
Which metal made the blue man blue?
a. Lead
b. Silver
c. Copper
d. Arsenic
e. mercury
B. Silver