Environment Flashcards

1
Q

soot (polycyclic aromatic hydrocarbons) at risk for

A
  • english chimney sweeps at risk for scrotal cancer (SCC)
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2
Q

vinyl chloride

A
  • plastic industry (make PVC pipes

- angiosarcoma of liver (also caused by arsenic

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3
Q

uranium and radon gas

A
  • miners

- lung cancer

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4
Q

β-napthylamine

A
  • dye makers and rubber workers; moth balls

- bladder cancer

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5
Q

benzoapyrene

A
  • steel mills and cigarette smoke

- lung and bladder cancer

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6
Q

carbon tetrachloride

A
  • liver breaks down to free radical CCl3
  • dry cleaners
  • liver and kidney toxicity
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7
Q

organophosphates

A
  • DUMBELSS
  • irreversible cholinesterase inhibitors
  • antidote = atropine + 2PAMM
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8
Q

angiosarcoma of liver caused by

A
  • V: vinyl chloride
  • A: arsenic
  • T: thorotrast
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9
Q

top 3 COD in smokers

A

heart disease, lung cancer, COPD (smokers get centriacinar emphysema)
- female smokers often develop early menopause bc knocks out estrogen –> have increased rate of postmenopausal osteoporosis

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10
Q

LSD

A
  • increased HR and BP
  • acute panic reaction and visual hallucinations
  • behavior-related trauma with possibly impulsive or irrational behavior
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11
Q

mescaline

A
  • in peyote

- similar to LSD but may also cause nausea/vomiting

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12
Q

MDMA

A
  • ecstasy
  • HTN, tachycardia, diaphoresis, dehydration
  • hyperthermia, rhabdomyolysis, myoglobinuric renal failure,
  • disseminated IV coagulation,
  • depleted brain serotonin
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13
Q

amphetamines

A
  • release of NE, dopamine, serotonin
  • produce similar effects to cocaine but are orally active
  • acute tox: disorientation, agitation, HTN, chest pain, palpitations, dry mouth, nausea, vomiting, diaphoresis, mydriasis (dilated eyes)
  • chronic tox: anorexia, pulmonary edema, stroke, eroded teeth, cellulitis, psychotic reactions
  • bath salts = designer drug w effects of amphetamines; highly addictive
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